| Literature DB >> 20036212 |
Natalya V Dudkina1, Roman Kouril, Katrin Peters, Hans-Peter Braun, Egbert J Boekema.
Abstract
The five complexes (complexes I-V) of the oxidative phosphorylation (OXPHOS) system of mitochondria can be extracted in the form of active supercomplexes. Single-particle electron microscopy has provided 2D and 3D data describing the interaction between complexes I and III, among I, III and IV and in a dimeric form of complex V, between two ATP synthase monomers. The stable interactions are called supercomplexes which also form higher-ordered oligomers. Cryo-electron tomography provides new insights on how these supercomplexes are arranged within intact mitochondria. The structure and function of OXPHOS supercomplexes are discussed.Mesh：
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Year: 2009 PMID： 20036212 DOI： 10.1016/j.bbabio.2009.12.013
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002