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Literature DB >> 20036195

IGF-1R targeted treatment of sarcoma.

Jeffrey A Toretsky, Richard Gorlick.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2009 PMID： 20036195 DOI： 10.1016/S1470-2045(09)70391-2

Source DB: PubMed Journal: Lancet Oncol ISSN： 1470-2045 Impact factor: 41.316

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Cited

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17 in total

Review 1. Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets.

Authors: Stephen L Lessnick; Marc Ladanyi
Journal: Annu Rev Pathol Date: 2011-09-19 Impact factor: 23.472

Review 2. Advances in sarcoma genomics and new therapeutic targets.

Authors: Barry S Taylor; Jordi Barretina; Robert G Maki; Cristina R Antonescu; Samuel Singer; Marc Ladanyi
Journal: Nat Rev Cancer Date: 2011-07-14 Impact factor: 60.716

3. Treatment of Bone Tumors.

Authors: Rajiv Rajani; C Parker Gibbs
Journal: Surg Pathol Clin Date: 2012-03

4. Targeted Therapy of Ewing's Sarcoma.

Authors: Vivek Subbiah; Pete Anderson
Journal: Sarcoma Date: 2010-10-31

5. The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs).

Authors: Maria A Pantaleo; Annalisa Astolfi; Margherita Nannini; Guido Biasco
Journal: J Transl Med Date: 2010-11-15 Impact factor: 5.531

6. PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathways.

Authors: Dan Lv; Jinye Liu; Lianying Guo; Dawei Wu; Ken Matsumoto; Lin Huang
Journal: Am J Cancer Res Date: 2016-01-15 Impact factor: 6.166

IGF-1R targeted treatment of sarcoma.

Review 1. Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets.

Review 2. Advances in sarcoma genomics and new therapeutic targets.

3. Treatment of Bone Tumors.

4. Targeted Therapy of Ewing's Sarcoma.

5. The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs).

6. PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathways.

7. Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.

8. Targeted therapy in Ewing sarcoma.

9. Akt and Hippo Pathways in Ewing's Sarcoma Tumors and Their Prognostic Significance.

Review 10. Molecular mechanisms underpinning sarcomas and implications for current and future therapy.