Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 ATP13A2 G2236A variant is rare in patients with early-onset Parkinson's disease and familial Parkinson's disease from Mainland China.

Literature DB >> 20036179

ATP13A2 G2236A variant is rare in patients with early-onset Parkinson's disease and familial Parkinson's disease from Mainland China.

X-Y Mao, J-M Burgunder, Z-J Zhang, X-L Chang, R Peng, J-M Burgunder, Y Yang, Y-C Wang, T Li, Z-J Zhang.

Abstract

Entities: Disease Gene Mutation Species

Mesh：

Substances：

Year: 2009 PMID： 20036179 DOI： 10.1016/j.parkreldis.2009.11.010

Source DB: PubMed Journal: Parkinsonism Relat Disord ISSN： 1353-8020 Impact factor: 4.891

Keyword Cloud
Cited

× No keyword cloud information.

6 in total

1. Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein.

Authors: Jieqiong Tan; Tongmei Zhang; Li Jiang; Jingwei Chi; Dongshen Hu; Qian Pan; Danling Wang; Zhuohua Zhang
Journal: J Biol Chem Date: 2011-07-01 Impact factor: 5.157

2. ATP13A2 deficiency disrupts lysosomal polyamine export.

Authors: Sarah van Veen; Shaun Martin; Chris Van den Haute; Veronick Benoy; Joseph Lyons; Roeland Vanhoutte; Jan Pascal Kahler; Jean-Paul Decuypere; Géraldine Gelders; Eric Lambie; Jeffrey Zielich; Johannes V Swinnen; Wim Annaert; Patrizia Agostinis; Bart Ghesquière; Steven Verhelst; Veerle Baekelandt; Jan Eggermont; Peter Vangheluwe
Journal: Nature Date: 2020-01-29 Impact factor: 49.962

ATP13A2 G2236A variant is rare in patients with early-onset Parkinson's disease and familial Parkinson's disease from Mainland China.

1. Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein.

2. ATP13A2 deficiency disrupts lysosomal polyamine export.

3. ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion.

4. ATP13A2 Gene Variants in Patients with Parkinson's Disease in Xinjiang.

Review 5. Mutations in the ATP13A2 gene and Parkinsonism: a preliminary review.

Review 6. The Emerging Role of the Lysosome in Parkinson's Disease.