| Literature DB >> 20035820 |
Gislaine Cristina Roma1, Karim Christina Scopinho Furquim, Gervásio Henrique Bechara, Maria Izabel Camargo-Mathias.
Abstract
The permethrin, active ingredient of the Advantage(R) Max3--Bayer, has been widely used in the chemical control of ticks. These ectoparasites are one of the most important animal groups that cause serious damage to their hosts. This study evaluated the toxic effects of permethrin in oocytes of Rhipicephalus sanguineus semi-engorged females subjected to four treatments: group I (control--distilled water), group II (206 ppm of permethrin), group III (1031 ppm of permethrin) and group IV (2062 ppm of permethrin). Results demonstrated that permethrin is a potent chemical agent causing major structural changes in oocytes, such as emergence of large vacuolated cytoplasm regions, reducing the amount of yolk granules and decreasing the size of oocytes, culminating with cell death. As reported in the literature, these oocytes changes, besides affect the tick nervous system, also drastically reduce or prevent the reproduction process in females of R. sanguineus ticks subjected to this compound. Copyright (c) 2009 Elsevier Ltd. All rights reserved.Entities:
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Year: 2009 PMID： 20035820 DOI： 10.1016/j.fct.2009.12.016
Source DB: PubMed Journal: Food Chem Toxicol ISSN： 0278-6915 Impact factor: 6.023