Literature DB >> 20035796

The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction.

Julia M Langton1, Rick Richardson.   

Abstract

Recent findings show that the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction is both context and stimulus specific. In this study we examined whether this switch was temporally specific as well. Re-extinction was found to be NMDAr-independent when it occurred 2 days after initial extinction but NMDAr-dependent when it occurred 21 days following initial extinction, thereby illustrating the importance of time as a type of context that modulates the mechanisms involved in extinction. Copyright 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID: 20035796     DOI: 10.1016/j.bbr.2009.12.018

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN: 0166-4328            Impact factor:   3.332


  7 in total

Review 1.  Pharmacological enhancement of fear reduction: preclinical models.

Authors:  Bronwyn M Graham; Julia M Langton; Rick Richardson
Journal:  Br J Pharmacol       Date:  2011-10       Impact factor: 8.739

2.  Interoceptive conditioning with nicotine using extinction and re-extinction to assess stimulus similarity with bupropion.

Authors:  Sergios Charntikov; Nicole R deWit; Rick A Bevins
Journal:  Neuropharmacology       Date:  2014-07-28       Impact factor: 5.250

3.  Opposing effects of D-cycloserine on fear despite a common extinction duration: interactions between brain regions and behavior.

Authors:  Scott S Bolkan; K Matthew Lattal
Journal:  Neurobiol Learn Mem       Date:  2013-12-27       Impact factor: 2.877

4.  Characterization of NMDAR-Independent Learning in the Hippocampus.

Authors:  Kaycie Kuss Tayler; Elizabeth Lowry; Kazumasa Tanaka; Brynne Levy; Leon Reijmers; Mark Mayford; Brian J Wiltgen
Journal:  Front Behav Neurosci       Date:  2011-05-18       Impact factor: 3.558

5.  Elucidating the mechanisms of fear extinction in developing animals: a special case of NMDA receptor-independent extinction in adolescent rats.

Authors:  Madelyne A Bisby; Kathryn D Baker; Rick Richardson
Journal:  Learn Mem       Date:  2018-03-15       Impact factor: 2.460

6.  From resilience to vulnerability: mechanistic insights into the effects of stress on transitions in critical period plasticity.

Authors:  Bridget L Callaghan; Bronwyn M Graham; Stella Li; Rick Richardson
Journal:  Front Psychiatry       Date:  2013-08-13       Impact factor: 4.157

7.  Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.

Authors:  Yuzhe Li; Ken Nakae; Shin Ishii; Honda Naoki
Journal:  PLoS Comput Biol       Date:  2016-09-12       Impact factor: 4.475

  7 in total

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