Literature DB >> 20035563

A phosphine-mediated construction of 1,4-oxazepines and 1,3-oxazines.

Céline François-Endelmond1, Thomas Carlin, Pierre Thuery, Olivier Loreau, Frédéric Taran.   

Abstract

A simple and efficient method for constructing 1,4-oxazepines and 1,3-oxazines was developed with use of a phosphine-mediated tandem reaction of ynones with 2-azido alcohols. The method offers a promising route to synthetically useful as well as biologically active heterocycles under mild conditions and may be exploited for the preparation of interesting chiral ligands.

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Year:  2010        PMID: 20035563     DOI: 10.1021/ol9024309

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Highly α-position regioselective ring-opening of epoxides catalyzed by halohydrin dehalogenase from Ilumatobacter coccineus: a biocatalytic approach to 2-azido-2-aryl-1-ols.

Authors:  Miao An; Wanyi Liu; Xiaoying Zhou; Ran Ma; Huihui Wang; Baodong Cui; Wenyong Han; Nanwei Wan; Yongzheng Chen
Journal:  RSC Adv       Date:  2019-05-24       Impact factor: 3.361

2.  Au-catalyzed skeletal rearrangement of O-propargylic oximes via N-O bond cleavage with the aid of a Brønsted base cocatalyst.

Authors:  Keigo Shiga; Ilya D Gridnev; Masahiro Terada; Itaru Nakamura
Journal:  Chem Sci       Date:  2019-04-18       Impact factor: 9.825

  2 in total

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