Literature DB >> 20035341

Near total thyroidectomy is an optimal treatment for graves' disease.

Antoine Digonnet1, Esther Willemse, Cécile Dekeyser, Luc Vandevelde, Moreau Michel, Daniel Glinoer, Denis Larsimont, Guy Andry.   

Abstract

Surgical management of Graves' disease is still debated. We report our current experience with thyroidectomy for Graves' disease at a tertiary center. A retrospective database of 132 patients who underwent surgery for Graves' disease from January 1985 to December 2008 was collected. During that period, 16 patients underwent subtotal thyroidectomy and 116 patients underwent near total thyroidectomy. Eighty-seven patients (66%) underwent surgery for recurrent disease after medical therapy. Forty-five patients (34%) had surgery as a primary treatment, the indications were large goiter size in 22 (17%), patient preference in 19 (14%), and associated cold nodule in 3 (2%). The incidence of cancer was 4.4%. Permanent hypoparathyroidism was observed in one patient who underwent a second surgery for recurrence. Unilateral transitory vocal cord palsy was observed in nine patients (7%), bilateral transitory vocal cord palsy was observed in one patient, and no definitive vocal cord palsy was observed. Two patients (1.5%) experienced post-operative hemorrhagia requiring surgical revision. Near total thyroidectomy for Graves' disease provides an immediate and definitive treatment with a low complication rate. Near total thyroidectomy offers an appropriate treatment for coexisting malignancy. This procedure can be safely recommended as a primary treatment, in experienced hands.

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Year:  2009        PMID: 20035341     DOI: 10.1007/s00405-009-1174-6

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  26 in total

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Authors:  Hideo Kurihara
Journal:  Thyroid       Date:  2002-03       Impact factor: 6.568

4.  Graves' disease: a long-term quality-of-life follow up of patients randomized to treatment with antithyroid drugs, radioiodine, or surgery.

Authors:  Mirna Abraham-Nordling; Ove Törring; Bertil Hamberger; Göran Lundell; Leif Tallstedt; Jan Calissendorff; Göran Wallin
Journal:  Thyroid       Date:  2005-11       Impact factor: 6.568

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6.  Total thyroidectomy is now the preferred option for the surgical management of Graves' disease.

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Journal:  Thyroid       Date:  2001-02       Impact factor: 6.568

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Journal:  World J Surg       Date:  2008-07       Impact factor: 3.352

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  5 in total

1.  Alternating from subtotal thyroid resection to total thyroidectomy in the treatment of Graves' disease prevents recurrences but increases the frequency of permanent hypoparathyroidism.

Authors:  Johannes Järhult; Per-Olof Andersson; Linda Duncker
Journal:  Langenbecks Arch Surg       Date:  2011-12-09       Impact factor: 3.445

2.  [Update hyperthyreoidism].

Authors:  L Möller; K Mann
Journal:  Internist (Berl)       Date:  2010-05       Impact factor: 0.743

3.  Disparity in the management of Graves' disease observed at an urban county hospital: a decade-long experience.

Authors:  Judy Jin; Victor Sandoval; Mary E Lawless; Ashwini R Sehgal; Christopher R McHenry
Journal:  Am J Surg       Date:  2012-02-07       Impact factor: 2.565

4.  [Graves' ophthalmopathy from the internist's perspective].

Authors:  K Laubner; W A Weber; J Seufert
Journal:  Ophthalmologe       Date:  2011-05       Impact factor: 1.059

5.  Total thyroidectomy as the single surgical option for benign and malignant thyroid disease: a surgical challenge.

Authors:  Ioannis Vassiliou; Aliki Tympa; Nikolaos Arkadopoulos; Fotios Nikolakopoulos; Thalia Petropoulou; Vassilios Smyrniotis
Journal:  Arch Med Sci       Date:  2013-02-18       Impact factor: 3.318

  5 in total

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