Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Inhibition of concanavalin A stimulation of feline lymphocytes by inactivated feline leukemia virus.

Literature DB >> 200353

Inhibition of concanavalin A stimulation of feline lymphocytes by inactivated feline leukemia virus.

Abstract

In a lymphocyte blast transformation assay, the response of feline lymphocytes to concanavalin A was suppressed 20 to 65 percent in the presence of inactivated feline leukemia virus. The decrease was not due to viral cytotoxicity, as determined by trypan blue viability counts, nor was the virus binding the concanavalin A and interfering with its mitogenic stimulation. The virus may be biochemically repressive in itself, interfering with cell-mediated immunity within the feline system.

Entities: Chemical Disease Species

Mesh：

Substances：
Concanavalin A

Year: 1977 PMID： 200353

Source DB: PubMed Journal: Cancer Res ISSN： 0008-5472 Impact factor: 12.701

Keyword Cloud
Cited

21 in total

Review 1. Feline leukemia virus: current status of the feline induced immune depression and immunoprevention.

Authors: R G Olsen; M G Lewis; L J Lafrado; L E Mathes; K Haffer; R Sharpee
Journal: Cancer Metastasis Rev Date: 1987 Impact factor: 9.264

Review 2. Mechanisms of virus-induced immune suppression.

Authors: M A Wainberg; E L Mills
Journal: Can Med Assoc J Date: 1985-06-01 Impact factor: 8.262

3. Nucleotide sequences of a feline leukemia virus subgroup A envelope gene and long terminal repeat and evidence for the recombinational origin of subgroup B viruses.

Authors: M A Stewart; M Warnock; A Wheeler; N Wilkie; J I Mullins; D E Onions; J C Neil
Journal: J Virol Date: 1986-06 Impact factor: 5.103

4. Suppressive effect on polyclonal B-cell activation of a synthetic peptide homologous to a transmembrane component of oncogenic retroviruses.

Authors: M Mitani; G J Cianciolo; R Snyderman; M Yasuda; R A Good; N K Day
Journal: Proc Natl Acad Sci U S A Date: 1987-01 Impact factor: 11.205

9. Suppression of human lymphocyte mitogen response by retroviruses of type D. I. Action of highly purified intact and disrupted virus.

Authors: J Denner; V Wunderlich; G Sydow
Journal: Arch Virol Date: 1985 Impact factor: 2.574

10. Inhibition by human T-lymphotropic virus (HTLV-I) of T-lymphocyte mitogenesis: failure of exogenous T-cell growth factor to restore responsiveness to lectin.

Authors: M A Wainberg; B Spira; M Boushira; R G Margolese
Journal: Immunology Date: 1985-01 Impact factor: 7.397

Inhibition of concanavalin A stimulation of feline lymphocytes by inactivated feline leukemia virus.

Review 1. Feline leukemia virus: current status of the feline induced immune depression and immunoprevention.

Review 2. Mechanisms of virus-induced immune suppression.

3. Nucleotide sequences of a feline leukemia virus subgroup A envelope gene and long terminal repeat and evidence for the recombinational origin of subgroup B viruses.

4. Suppressive effect on polyclonal B-cell activation of a synthetic peptide homologous to a transmembrane component of oncogenic retroviruses.

5. Antigenic modification: its relation to protective host resistance in murine salmonellosis.

6. Reversible interference with TCGF activity by virus particles.

7. Viral abrogation of lymphocyte mitogenesis: induction of a soluble factor inhibitory to cellular proliferation.

8. Animal model of human disease: leukemic lymphoma.

9. Suppression of human lymphocyte mitogen response by retroviruses of type D. I. Action of highly purified intact and disrupted virus.

10. Inhibition by human T-lymphotropic virus (HTLV-I) of T-lymphocyte mitogenesis: failure of exogenous T-cell growth factor to restore responsiveness to lectin.