| Literature DB >> 20034423 |
Marco Nadalini1, Nicoletta Tarozzi, Vincenzo Distratis, Giulia Scaravelli, Andrea Borini.
Abstract
To date, several publications have focused their attention on a new method for observing spermatozoa called 'motile sperm organelle morphology examination' (MSOME), which enables the evaluation of the fine nuclear morphology of motile spermatozoa in real time at high magnification (>x6000). As a consequence, a new microinjection procedure called intracytoplasmic morphologically selected sperm injection (IMSI) has been developed. The aim of the present work is therefore to evaluate the efficacy of the IMSI technique in the light of the current literature, focusing attention on the potential clinical application of the selection of strictly morphologically normal spermatozoa in patients undergoing conventional intracytoplasmic sperm injection treatments. In addition, a brief analysis of preliminary data regarding the relationship between IMSI and assisted reproduction treatment outcome is presented.Entities:
Mesh:
Year: 2009 PMID: 20034423 DOI: 10.1016/s1472-6483(10)60283-0
Source DB: PubMed Journal: Reprod Biomed Online ISSN: 1472-6483 Impact factor: 3.828