Literature DB >> 20033656

Use of inbred mouse strains to map recognition receptors of MCMV infected cells in the NK cell gene locus.

Nassima Fodil-Cornu1, Michal Pyzik, Silvia M Vidal.   

Abstract

Genetically distinct inbred strains of mice that differ in their susceptibility to mouse cytomegalovirus (MCMV) are invaluable for dissecting complex host-pathogen interactions. Their study has allowed the identification of host-resistance loci, including several activating NK cell receptors of major histocompatibility complex (MHC) class I. In this chapter, we provide a practical guide to the genetic mapping and functional characterization of NK cell receptors that control innate immunity against MCMV via specific recognition of infected cells.

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Year:  2010        PMID： 20033656     DOI： 10.1007/978-1-60761-362-6_27

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  3 in total

1.  Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains.

Authors:  Michał Pyzik; Benoit Charbonneau; Eve-Marie Gendron-Pontbriand; Marina Babić; Astrid Krmpotić; Stipan Jonjić; Silvia M Vidal
Journal:  J Exp Med       Date:  2011-04-25       Impact factor: 14.307

2.  NK cell receptor/H2-Dk-dependent host resistance to viral infection is quantitatively modulated by H2q inhibitory signals.

Authors:  Nassima Fodil-Cornu; J Concepción Loredo-Osti; Silvia M Vidal
Journal:  PLoS Genet       Date:  2011-04-21       Impact factor: 5.917

3.  TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy.

Authors:  Jeffrey P Marcoe; James R Lim; Keri L Schaubert; Nassima Fodil-Cornu; Marsel Matka; Alexandra L McCubbrey; Alexander R Farr; Silvia M Vidal; Yasmina Laouar
Journal:  Nat Immunol       Date:  2012-08-05       Impact factor: 25.606
  3 in total

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