Literature DB >> 2003334

Chemical mutagenesis and fine-structure functional analysis of the mouse genome.

E M Rinchik1.   

Abstract

Heritable mutations constitute important raw materials for mammalian developmental genetics and general genome studies. Mutations induced by high-efficiency chemical mutagenesis of germ cells in mice can be used in genetic and molecular studies to complement physical-mapping strategies and to examine the nature and extent of the functional complexities hidden within the mammalian genome.

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Year:  1991        PMID： 2003334     DOI： 10.1016/0168-9525(91)90016-j

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  27 in total

1.  A large-scale insertional mutagenesis screen in zebrafish.

Authors:  A Amsterdam; S Burgess; G Golling; W Chen; Z Sun; K Townsend; S Farrington; M Haldi; N Hopkins
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

2.  N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: Completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations.

Authors:  E M Rinchik; D A Carpenter
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

3.  Rapid generation of nested chromosomal deletions on mouse chromosome 2.

Authors:  D F LePage; D M Church; E Millie; T J Hassold; R A Conlon
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-12       Impact factor: 11.205

4.  Genetic, cytogenetic, and molecular analyses of mutations induced by melphalan demonstrate high frequencies of heritable deletions and other rearrangements from exposure of postspermatogonial stages of the mouse.

Authors:  L B Russell; P R Hunsicker; N L Cacheiro; E M Rinchik
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-01       Impact factor: 11.205

5.  Genetic and molecular analysis of recessive alleles at the pink-eyed dilution (p) locus of the mouse.

Authors:  M F Lyon; T R King; Y Gondo; J M Gardner; Y Nakatsu; E M Eicher; M H Brilliant
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

6.  Physical analysis of murine albino deletions that disrupt liver-specific gene regulation or mesoderm development.

Authors:  M L Klebig; B S Kwon; E M Rinchik
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

7.  Identification of mutations from phenotype-driven ENU mutagenesis in mouse chromosome 7.

Authors:  Cymbeline T Culiat; Mitchell L Klebig; Zhaowei Liu; Heidi Monroe; Beverly Stanford; Jayashree Desai; Samvit Tandan; Lori Hughes; Marilyn K Kerley; Donald A Carpenter; Dabney K Johnson; Eugene M Rinchik; Qingbo Li
Journal:  Mamm Genome       Date:  2005-08       Impact factor: 2.957

Review 8.  N-ethyl-N-nitrosourea mutagenesis: boarding the mouse mutant express.

Authors:  Sabine P Cordes
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

9.  Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells.

Authors:  G Luo; Z Ivics; Z Izsvák; A Bradley
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

Review 10.  Mouse models of genetic disease: new approaches, new paradigms.

Authors:  S D Brown
Journal:  J Inherit Metab Dis       Date:  1998-08       Impact factor: 4.982
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