Literature DB >> 20033195

Treatment of velopharyngeal insufficiency by autologous fat injection.

Igor Leuchter1, Valérie Schweizer, Judith Hohlfeld, Philippe Pasche.   

Abstract

Velopharyngeal insufficiency (VPI) is a structural or functional trouble, which causes hypernasal speech. Velopharyngeal flaps, speech therapy and augmentation pharyngoplasty, using different implants, have all been used to address this trouble. We hereby present our results following rhinopharyngeal autologous fat injection in 18 patients with mild velopharyngeal insufficiency (12 soft palate clefts, 4 functional VPI, 2 myopathy). 28 injections were carried out between 2004 and 2007. The degree of hypernasal speech was evaluated pre- and postoperatively by a speech therapist and an ENT specialist and quantified by an acoustic nasometry (Kay Elemetrics). All patients were exhaustively treated with preoperative speech therapy (average, 8 years). The mean value of the nasalance score was 37% preoperatively and 23% postoperatively (p = 0.015). The hypernasality was reduced postoperatively in all patients (1-3 degrees of the Borel-Maisonny score). There were no major complications, two minor complications (one hematoma, one cervical pain). The autologous fat injection is a simple, safe, minimally invasive procedure. It proves to be efficient in cases of mild velopharyngeal insufficiency or after a suboptimal velopharyngoplasty.

Entities:  

Mesh:

Year:  2009        PMID: 20033195     DOI: 10.1007/s00405-009-1157-7

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  33 in total

1.  Adipose tissue processed for lipoinjection shows increased cellular survival in vitro when tissue engineering principles are applied.

Authors:  Fredrik R M Huss; Gunnar Kratz
Journal:  Scand J Plast Reconstr Surg Hand Surg       Date:  2002

2.  "Nasalance" vs. listner judgements of nasality.

Authors:  S G Fletcher
Journal:  Cleft Palate J       Date:  1976-01

3.  Migration of Teflon after vocal cord injection.

Authors:  J C Ellis; T V McCaffrey; L W DeSanto; H V Reiman
Journal:  Otolaryngol Head Neck Surg       Date:  1987-01       Impact factor: 3.497

4.  Surgical management of velopharyngeal dysfunction: outcome analysis of autogenous posterior pharyngeal wall augmentation.

Authors:  P D Witt; T G O'Daniel; J L Marsh; L M Grames; H R Muntz; T K Pilgram
Journal:  Plast Reconstr Surg       Date:  1997-04       Impact factor: 4.730

5.  Improvement of velopharyngeal insufficiency by teflon injection.

Authors:  P H Ward; R Stoudt; R Goldman
Journal:  Trans Am Acad Ophthalmol Otolaryngol       Date:  1967 Nov-Dec

6.  Misadventures with injectable polytef (Teflon).

Authors:  H J Rubin
Journal:  Arch Otolaryngol       Date:  1975-02

7.  The classic reprint. Concerning a subcutaneous prosthesis: Robert Gersuny. (Uber eine subcutane Prothese. Zeitschrift f. Heilkunde Wien u Leipzig 21:199, 1900.). Translated from the German by Miss Rita Euerle.

Authors: 
Journal:  Plast Reconstr Surg       Date:  1980-04       Impact factor: 4.730

8.  Autologous fat injection for soft tissue augmentation in the face: a safe procedure?

Authors:  D L Feinendegen; R W Baumgartner; P Vuadens; G Schroth; H P Mattle; F Regli; H Tschopp
Journal:  Aesthetic Plast Surg       Date:  1998 May-Jun       Impact factor: 2.326

9.  Long-term result of vocal cord augmentation with autogenous fat.

Authors:  C A Bauer; J Valentino; H T Hoffman
Journal:  Ann Otol Rhinol Laryngol       Date:  1995-11       Impact factor: 1.547

Review 10.  Autologous fat transfer for facial recontouring: is there science behind the art?

Authors:  Matthew R Kaufman; Timothy A Miller; Catherine Huang; Jason Roostaeian; Jason Roostaien; Kristy L Wasson; Rebekah K Ashley; James P Bradley
Journal:  Plast Reconstr Surg       Date:  2007-06       Impact factor: 4.730

View more
  13 in total

1.  Intravelar and Extravelar Portions of Soft Palate Muscles in Velic Constrictions: A Three-Dimensional Modeling Study.

Authors:  Peter Anderson; Sidney Fels; Ian Stavness; William G Pearson; Bryan Gick
Journal:  J Speech Lang Hear Res       Date:  2019-04-15       Impact factor: 2.297

Review 2.  Applications of Fat Grafting in Pediatric Patients.

Authors:  Linden Shih; Amjed Abu-Ghname; Matthew J Davis; Amy S Xue; Robert F Dempsey; Edward P Buchanan
Journal:  Semin Plast Surg       Date:  2020-02-15       Impact factor: 2.314

3.  Adipose-derived stem cell (ASC)-enriched fat grafting: experiments using White rabbits and an automated cell processing apparatus.

Authors:  Natsuko Kakudo; Naoki Morimoto; Takeshi Ogawa; Masakatsu Hihara; Fangyuan Lai; Kenji Kusumoto
Journal:  Med Mol Morphol       Date:  2017-04-24       Impact factor: 2.309

4.  Rhinopharyngeal autologous fat injection for treatment of velopharyngeal insufficiency in patients with cleft palate.

Authors:  Elsa Piotet; Céline Beguin; Martin Broome; Katia Iglesias; Frédéric Olivier; Igor Leuchter; Chantal Zbinden; Judith Hohlfeld; Anthony de Buys Roessingh; Valérie Schweizer; Philippe Pasche
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-11-20       Impact factor: 2.503

5.  Autologous fat injection to face and neck: from soft tissue augmentation to regenerative medicine.

Authors:  R F Mazzola; G Cantarella; S Torretta; A Sbarbati; L Lazzari; L Pignataro
Journal:  Acta Otorhinolaryngol Ital       Date:  2011-04       Impact factor: 2.124

Review 6.  In search of the optimal surgical treatment for velopharyngeal dysfunction in 22q11.2 deletion syndrome: a systematic review.

Authors:  Nicole E Spruijt; Judith Reijmanhinze; Greet Hens; Vincent Vander Poorten; Aebele B Mink van der Molen
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

7.  Results and complications of 1104 surgeries for velopharyngeal insufficiency.

Authors:  Jenő Hirschberg
Journal:  ISRN Otolaryngol       Date:  2012-04-11

8.  Adipose-derived regenerative cell (ADRC)-enriched fat grafting: optimal cell concentration and effects on grafted fat characteristics.

Authors:  Natsuko Kakudo; Yoshihito Tanaka; Naoki Morimoto; Takeshi Ogawa; Satoshi Kushida; Tomoya Hara; Kenji Kusumoto
Journal:  J Transl Med       Date:  2013-10-10       Impact factor: 5.531

9.  Injection Pharyngoplasty With a Hyaluronic Acid and Dextranomer Copolymer to Treat Velopharyngeal Insufficiency in Adults.

Authors:  Brandon W Peck; Becky S Baas; Shelagh A Cofer
Journal:  Mayo Clin Proc Innov Qual Outcomes       Date:  2017-08-02

10.  Autologous fat grafting in the treatment of velopharyngeal insufficiency: Clinical outcomes and treatment tolerability survey in a case series of 21 patients.

Authors:  Renzo Panizza; Marco Ghiglione; Enrico Maria Zingarelli; Michela Massa; Claudio Carlini; Rossella Arnoldi; Alessio Pini Prato; Silvia Scarrone; Francesco Vaccarella
Journal:  Indian J Plast Surg       Date:  2018 May-Aug
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.