Literature DB >> 20031402

Molecular design of small organic molecules based on structural information for a conformationally constrained peptide that binds to G-CSF receptor.

Radwan El-Haggar1, Ken Kamikawa, Kazuya Machi, Zhengmao Ye, Yuko Ishino, Takeshi Tsumuraya, Ikuo Fujii.   

Abstract

Based on structural information for a peptide (P8-2KAQ) that binds to granulocyte-colony stimulating factor receptor (G-CSFR), small ligands with a biaryl scaffold were designed and their binding affinities were evaluated. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 20031402     DOI： 10.1016/j.bmcl.2009.12.010

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  "Human and Mouse Cross-Reactive" Albumin-Binding Helix-Loop-Helix Peptide Tag for Prolonged Bioactivity of Therapeutic Proteins.

Authors:  Yuto Nakatani; Zhengmao Ye; Yuki Ishizue; Taishi Higashi; Teruko Imai; Ikuo Fujii; Masataka Michigami
Journal:  Mol Pharm       Date:  2022-05-28       Impact factor: 5.364

2.  Chemical Modification of Phage-Displayed Helix-Loop-Helix Peptides to Construct Kinase-Focused Libraries.

Authors:  Daisuke Fujiwara; Kousuke Mihara; Ryo Takayama; Yusuke Nakamura; Mitsuhiro Ueda; Takeshi Tsumuraya; Ikuo Fujii
Journal:  Chembiochem       Date:  2021-10-19       Impact factor: 3.461

3.  High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system.

Authors:  Nobuo Yoshimoto; Kenji Tatematsu; Masumi Iijima; Tomoaki Niimi; Andrés D Maturana; Ikuo Fujii; Akihiko Kondo; Katsuyuki Tanizawa; Shun'ichi Kuroda
Journal:  Sci Rep       Date:  2014-02-28       Impact factor: 4.379
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.