Literature DB >> 20031365

Cerebral venous sinus thrombosis in the emergency department: retrospective analysis of 17 cases and review of the literature.

Christopher Fischer1, Joshua Goldstein, Jonathan Edlow.   

Abstract

BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a rare but serious cause of neurologic impairment. Due to its relative rarity, there is limited research that describes the incidence and clinical features of CVST in the emergency department (ED).
OBJECTIVES: To describe the demographic, clinical, and historical characteristics of patients with CVST who were initially seen in the ED.
METHODS: This is a retrospective analysis of all patients presenting to three urban, tertiary care hospitals between January 2001 and December 2005 who were diagnosed with CVST. Patients were excluded if they were transferred from other hospitals, or admitted directly to the hospital without evaluation in the ED. We use one representative case to describe the presentation, evaluation, and treatment of CVST.
RESULTS: Seventeen patients met the inclusion criteria. Patients had a mean age of 42 years. Presenting complaints included headache (70%), focal neurologic complaints (numbness, weakness, aphasia) (29%), seizure (24%), and head injury (12%). Ninety-four percent of patients had a focal neurologic finding in the ED. A likely contributing cause of thrombosis was identified in all but one patient. More than half of the patients had been evaluated in the ED in the previous 60 days. Two patients died, both as a result of their thrombosis and resulting cerebral infarctions and edema. Of the patients who survived, 80% had a good functional outcome.
CONCLUSIONS: CVST is rare, but it can have significant associated morbidity and mortality. Whereas the clinical outcome and functional outcomes of treated patients can vary, prompt recognition of the disease is important. Copyright (c) 2010 Elsevier Inc. All rights reserved.

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Year:  2009        PMID: 20031365     DOI: 10.1016/j.jemermed.2009.08.061

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  9 in total

Review 1.  Headache in the emergency department.

Authors:  Benjamin W Friedman; Richard B Lipton
Journal:  Curr Pain Headache Rep       Date:  2011-08

2.  Headache in a young male: the clot thickens.

Authors:  Charles Philip Miller; Jonathan Stedman; Kiruba Nagaratnam; Robert Gray
Journal:  BMJ Case Rep       Date:  2013-05-22

3.  Evaluation of plasma D-dimer plus fibrinogen in predicting acute CVST.

Authors:  Ran Meng; Xiaoying Wang; Mohammed Hussain; David Dornbos; Lu Meng; Yu Liu; Yan Wu; Mingming Ning; Buonanno Ferdinando S; Eng H Lo; Yuchuan Ding; Xunming Ji
Journal:  Int J Stroke       Date:  2013-03-19       Impact factor: 5.266

4.  Misdiagnosis of Cerebral Vein Thrombosis in the Emergency Department.

Authors:  Ava L Liberman; Gino Gialdini; Ekaterina Bakradze; Abhinaba Chatterjee; Hooman Kamel; Alexander E Merkler
Journal:  Stroke       Date:  2018-04-25       Impact factor: 7.914

5.  Clinical associations, biological risk factors and outcomes of cerebral venous sinus thrombosis.

Authors:  Hafize Nalan Gunes; Burcu Gokce Cokal; Selda Keskin Guler; Tahir Kurtulus Yoldas; Umit Yavuz Malkan; Cemile Sencer Demircan; Mehmet Ilker Yon; Zeynep Yoldas; Gursel Gunes; Ibrahim Celalettin Haznedaroglu
Journal:  J Int Med Res       Date:  2016-11-10       Impact factor: 1.671

6.  Abducens Palsy Due to Cerebral Venous Sinus Thrombosis in a Patient with Heart Failure.

Authors:  Cem Özgönül; Osman Melih Ceylan; Fatih Mehmet Mutlu; Halil İbrahim Altınsoy; Mustafa Aparcı
Journal:  Turk J Ophthalmol       Date:  2015-08-05

Review 7.  Cerebral sinus venous thrombosis.

Authors:  Hernando Raphael Alvis-Miranda; Sandra Milena Castellar-Leones; Gabriel Alcala-Cerra; Luis Rafael Moscote-Salazar
Journal:  J Neurosci Rural Pract       Date:  2013-10

8.  Simultaneous Multiple Thromboembolic Events in a Postpartum Patient.

Authors:  Ibtisam Ghashimi; Linda Jafarah; Amal Bakhsh; Ahmed Azzazy; Ahmed Royashed; Awad Awad; Ahmed Ramadan; Ghofran Hashimi; Refah Alqahtani; Abdullah Bakhsh
Journal:  Clin Pract Cases Emerg Med       Date:  2018-06-16

Review 9.  Seizure in cerebral venous and sinus thrombosis.

Authors:  Jafar Mehvari Habibabadi; Mohammad Saadatnia; Nasim Tabrizi
Journal:  Epilepsia Open       Date:  2018-06-08
  9 in total

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