Literature DB >> 20030462

Did acetaminophen provoke the autism epidemic?

Peter Good1.   

Abstract

Schultz et al (2008) raised the question whether regression into autism is triggered, not by the measles-mumps-rubella (MMR) vaccine, but by acetaminophen (Tylenol) given for its fever and pain. Considerable evidence supports this contention, most notably the exponential rise in the incidence of autism since 1980, when acetaminophen began to replace aspirin for infants and young children. The impetus for this shift - a Centers for Disease Control and Prevention warning that aspirin was associated with Reye's syndrome - has since been compellingly debunked. If aspirin is not to be feared as a cause of Reyes syndrome, and acetaminophen is to be feared as a cause of autism, can the autism epidemic be reversed by replacing acetaminophen with aspirin or other remedies?

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Year:  2009        PMID: 20030462

Source DB:  PubMed          Journal:  Altern Med Rev        ISSN: 1089-5159


  5 in total

1.  Alterations in Synaptic Plasticity and Oxidative Stress Following Long-Term Paracetamol Treatment in Rat Brain.

Authors:  Laddawan Lalert; Wilawan Ji-Au; Sirinapa Srikam; Tipthanan Chotipinit; Sompol Sanguanrungsirikul; Anan Srikiatkhachorn; Supang Maneesri-le Grand
Journal:  Neurotox Res       Date:  2019-07-30       Impact factor: 3.911

Review 2.  Environmental factors associated with autism spectrum disorder: a scoping review for the years 2003-2013.

Authors:  M Ng; J G de Montigny; M Ofner; M T Do
Journal:  Health Promot Chronic Dis Prev Can       Date:  2017-01       Impact factor: 3.240

3.  A model for the induction of autism in the ecosystem of the human body: the anatomy of a modern pandemic?

Authors:  Staci D Bilbo; Cynthia D Nevison; William Parker
Journal:  Microb Ecol Health Dis       Date:  2015-01-28

Review 4.  Extrahepatic toxicity of acetaminophen: critical evaluation of the evidence and proposed mechanisms.

Authors:  Stefanie Kennon-McGill; Mitchell R McGill
Journal:  J Clin Transl Res       Date:  2017-11-18

Review 5.  Potential Role of Selenoenzymes and Antioxidant Metabolism in relation to Autism Etiology and Pathology.

Authors:  Laura J Raymond; Richard C Deth; Nicholas V C Ralston
Journal:  Autism Res Treat       Date:  2014-03-05
  5 in total

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