Literature DB >> 20029853

Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation.

Ishu Saraogi1, James A Hebda, Jorge Becerril, Lara A Estroff, Andrew D Miranker, Andrew D Hamilton.   

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Year:  2010        PMID： 20029853      PMCID： PMC2872138          DOI： 10.1002/anie.200901694

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  30 in total

1.  A possible role for pi-stacking in the self-assembly of amyloid fibrils.

Authors:  Ehud Gazit
Journal:  FASEB J       Date:  2002-01       Impact factor: 5.191

Review 2.  Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

Authors:  Byron Caughey; Peter T Lansbury
Journal:  Annu Rev Neurosci       Date:  2003-04-09       Impact factor: 12.449

3.  Design of a synthetic foldamer that modifies the growth of calcite crystals.

Authors:  Lara A Estroff; Christopher D Incarvito; Andrew D Hamilton
Journal:  J Am Chem Soc       Date:  2004-01-14       Impact factor: 15.419

4.  Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex.

Authors:  Justin T Ernst; Jorge Becerril; Hyung Soon Park; Hang Yin; Andrew D Hamilton
Journal:  Angew Chem Int Ed Engl       Date:  2003-02-03       Impact factor: 15.336

5.  Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

Authors:  Jacqueline F Aitken; Kerry M Loomes; Barbara Konarkowska; Garth J S Cooper
Journal:  Biochem J       Date:  2003-09-15       Impact factor: 3.857

Review 6.  Progress towards a molecular-level structural understanding of amyloid fibrils.

Authors:  Robert Tycko
Journal:  Curr Opin Struct Biol       Date:  2004-02       Impact factor: 6.809

Review 7.  Therapeutic approaches to protein-misfolding diseases.

Authors:  Fred E Cohen; Jeffery W Kelly
Journal:  Nature       Date:  2003-12-18       Impact factor: 49.962

8.  Phospholipid catalysis of diabetic amyloid assembly.

Authors:  Jefferson D Knight; Andrew D Miranker
Journal:  J Mol Biol       Date:  2004-08-27       Impact factor: 5.469

9.  Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.

Authors:  Alexandra E Butler; Jennifer Jang; Tatyana Gurlo; Maynard D Carty; Walter C Soeller; Peter C Butler
Journal:  Diabetes       Date:  2004-06       Impact factor: 9.461

Review 10.  Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes.

Authors:  Rebecca L Hull; Gunilla T Westermark; Per Westermark; Steven E Kahn
Journal:  J Clin Endocrinol Metab       Date:  2004-08       Impact factor: 5.958
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  35 in total

1.  Peptide Conjugates of Benzene Carboxylic Acids as Agonists and Antagonists of Amylin Aggregation.

Authors:  Adam A Profit; Jayson Vedad; Ruel Z B Desamero
Journal:  Bioconjug Chem       Date:  2017-01-27       Impact factor: 4.774

2.  Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment.

Authors:  Ravi Prakash Reddy Nanga; Jeffrey R Brender; Subramanian Vivekanandan; Ayyalusamy Ramamoorthy
Journal:  Biochim Biophys Acta       Date:  2011-06-23

Review 3.  Inhibition of α-helix-mediated protein-protein interactions using designed molecules.

Authors:  Valeria Azzarito; Kérya Long; Natasha S Murphy; Andrew J Wilson
Journal:  Nat Chem       Date:  2013-03       Impact factor: 24.427

4.  Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes.

Authors:  Idira Obasse; Mark Taylor; Nigel J Fullwood; David Allsop
Journal:  Interface Focus       Date:  2017-10-20       Impact factor: 3.906

5.  A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc.

Authors:  Samer Salamekh; Jeffrey R Brender; Suk-Joon Hyung; Ravi Prakash Reddy Nanga; Subramanian Vivekanandan; Brandon T Ruotolo; Ayyalusamy Ramamoorthy
Journal:  J Mol Biol       Date:  2011-05-17       Impact factor: 5.469

6.  Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics.

Authors:  Sunil Kumar; Diana E Schlamadinger; Mark A Brown; Joanna M Dunn; Brandon Mercado; James A Hebda; Ishu Saraogi; Elizabeth Rhoades; Andrew D Hamilton; Andrew D Miranker
Journal:  Chem Biol       Date:  2015-03-05

Review 7.  Implications of peptide assemblies in amyloid diseases.

Authors:  Pu Chun Ke; Marc-Antonie Sani; Feng Ding; Aleksandr Kakinen; Ibrahim Javed; Frances Separovic; Thomas P Davis; Raffaele Mezzenga
Journal:  Chem Soc Rev       Date:  2017-10-30       Impact factor: 54.564

Review 8.  Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.

Authors:  Ping Cao; Peter Marek; Harris Noor; Vadim Patsalo; Ling-Hsien Tu; Hui Wang; Andisheh Abedini; Daniel P Raleigh
Journal:  FEBS Lett       Date:  2013-02-01       Impact factor: 4.124

9.  Large-scale and chromatography-free synthesis of an octameric quinoline-based aromatic amide helical foldamer.

Authors:  Ting Qi; Tiny Deschrijver; Ivan Huc
Journal:  Nat Protoc       Date:  2013-03-14       Impact factor: 13.491

10.  A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes.

Authors:  James A Hebda; Ishu Saraogi; Mazin Magzoub; Andrew D Hamilton; Andrew D Miranker
Journal:  Chem Biol       Date:  2009-09-25
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