PURPOSE: To report a case of fungal keratitis caused by Colletotrichum gloeosporioides, which is a rare pathogen in humans. METHODS: An 80-year-old woman developed fungal keratitis after having sustained a traumatic injury during field work. The patient was initially examined by slit-lamp biomicroscopy and the Heidelberg Retina Tomograph II-Rostock Cornea Module (HRT II-RCM). Corneal scrapings were collected and submitted for laboratory investigations. RESULTS: Many septate, hyphae-like interlocking and branching white lines were observed in the area of the infiltrate by HRT II-RCM. A tentative diagnosis of fungal keratitis was made, and the patient was treated with systemic and topical voriconazole and pimaricin ophthalmic ointment. The infectious focus resolved within 2 weeks, and there were no signs of a recurrence after 3 months of treatment with the antifungal agents. The culture of the corneal scraping grew C. gloeosporioides. CONCLUSIONS: HRT II-RCM was useful in detecting filamentous fungi in the cornea. The treatment with voriconazole and pimaricin was effective in the treatment of C. gloeosporioides keratitis.
PURPOSE: To report a case of fungal keratitis caused by Colletotrichum gloeosporioides, which is a rare pathogen in humans. METHODS: An 80-year-old woman developed fungal keratitis after having sustained a traumatic injury during field work. The patient was initially examined by slit-lamp biomicroscopy and the Heidelberg Retina Tomograph II-Rostock Cornea Module (HRT II-RCM). Corneal scrapings were collected and submitted for laboratory investigations. RESULTS: Many septate, hyphae-like interlocking and branching white lines were observed in the area of the infiltrate by HRT II-RCM. A tentative diagnosis of fungal keratitis was made, and the patient was treated with systemic and topical voriconazole and pimaricin ophthalmic ointment. The infectious focus resolved within 2 weeks, and there were no signs of a recurrence after 3 months of treatment with the antifungal agents. The culture of the corneal scraping grew C. gloeosporioides. CONCLUSIONS: HRT II-RCM was useful in detecting filamentous fungi in the cornea. The treatment with voriconazole and pimaricin was effective in the treatment of C. gloeosporioideskeratitis.
Authors: Victoria Squissato; Yeni H Yucel; Susan E Richardson; Alaa Alkhotani; David T Wong; Navdeep Nijhawan; Clara C Chan Journal: Med Mycol Case Rep Date: 2015-06-05
Authors: Reina Llamos; Abdullah M S Al-Hatmi; Gerardo Martínez; Ferry Hagen; Rosario Velar; Alexeide de la Caridad Castillo Pérez; Jacques F Meis; María T Illnait-Zaragozí Journal: JMM Case Rep Date: 2016-08-30