Literature DB >> 20028000

Total synthesis of uniflorine A, casuarine, australine, 3-epi-australine, and 3,7-di-epi-australine from a common precursor.

Thunwadee Ritthiwigrom1, Anthony C Willis, Stephen G Pyne.   

Abstract

A flexible method for the diastereoselective total synthesis of the pyrrolizidine alkaloids uniflorine A, casuarine, australine, and 3-epi-australine and the unnatural epimer 3,7-di-epi-australine from a common chiral 2,5-dihydropyrrole precursor is described.

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Year:  2010        PMID： 20028000     DOI： 10.1021/jo902355p

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Catalytic diastereoselective petasis reactions.

Authors:  Giovanni Muncipinto; Philip N Moquist; Stuart L Schreiber; Scott E Schaus
Journal:  Angew Chem Int Ed Engl       Date:  2011-07-12       Impact factor: 15.336

Review 2.  Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications.

Authors:  Manar Ahmed Fouad; Hamida Abdel-Hamid; Mohammed Salah Ayoup
Journal:  RSC Adv       Date:  2020-11-23       Impact factor: 4.036

3.  Glycerol as an efficient medium for the petasis borono-mannich reaction.

Authors:  Tomi Rosholm; Pedro M P Gois; Robert Franzen; Nuno R Candeias
Journal:  ChemistryOpen       Date:  2014-10-18       Impact factor: 2.911

4.  Reactivity and Synthetic Applications of Multicomponent Petasis Reactions.

Authors:  Peng Wu; Michael Givskov; Thomas E Nielsen
Journal:  Chem Rev       Date:  2019-08-27       Impact factor: 60.622

Review 5.  Metal-mediated synthesis of pyrrolines.

Authors:  Noelia S Medran; Agustina La-Venia; Sebastian A Testero
Journal:  RSC Adv       Date:  2019-02-27       Impact factor: 4.036
  5 in total

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