AIM: To compare a first diagnostic procedure of transbronchial needle aspiration (TBNA) with selection of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or TBNA for mediastinal lymphadenopathy. METHODS: Sixty-eight consecutive patients with mediastinal lymphadenopathy on computed tomography (CT), who required cytopathological diagnosis, were recruited. The first 34 underwent a sequential approach in which TBNA was performed first, followed by EUS-FNA if TBNA was unrevealing. The next 34 underwent a selective approach where either TBNA or EUS-FNA was selected as the first procedure based on the CT findings. RESULTS: The diagnostic yield of TBNA as the first diagnostic procedure in the sequential approach was 62%. In the selective approach, the diagnostic yield of the first procedure was 71%. There was no significant difference in the overall diagnostic yield, but there were significantly fewer combined procedures with the selective approach. CONCLUSION: Selecting either EUS-FNA or TBNA as the first diagnostic procedure achieved a comparable diagnostic yield with significantly fewer procedures than performing TBNA first in all patients.
AIM: To compare a first diagnostic procedure of transbronchial needle aspiration (TBNA) with selection of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or TBNA for mediastinal lymphadenopathy. METHODS: Sixty-eight consecutive patients with mediastinal lymphadenopathy on computed tomography (CT), who required cytopathological diagnosis, were recruited. The first 34 underwent a sequential approach in which TBNA was performed first, followed by EUS-FNA if TBNA was unrevealing. The next 34 underwent a selective approach where either TBNA or EUS-FNA was selected as the first procedure based on the CT findings. RESULTS: The diagnostic yield of TBNA as the first diagnostic procedure in the sequential approach was 62%. In the selective approach, the diagnostic yield of the first procedure was 71%. There was no significant difference in the overall diagnostic yield, but there were significantly fewer combined procedures with the selective approach. CONCLUSION: Selecting either EUS-FNA or TBNA as the first diagnostic procedure achieved a comparable diagnostic yield with significantly fewer procedures than performing TBNA first in all patients.
Authors: M B Wallace; G A Silvestri; A V Sahai; R H Hawes; B J Hoffman; V Durkalski; W S Hennesey; C E Reed Journal: Ann Thorac Surg Date: 2001-12 Impact factor: 4.330
Authors: E M Harrow; W Abi-Saleh; J Blum; T Harkin; S Gasparini; D J Addrizzo-Harris; A C Arroliga; G Wight; A C Mehta Journal: Am J Respir Crit Care Med Date: 2000-02 Impact factor: 21.405
Authors: A Fritscher-Ravens; P V Sriram; C Bobrowski; A Pforte; T Topalidis; C Krause; S Jaeckle; F Thonke; N Soehendra Journal: Am J Gastroenterol Date: 2000-09 Impact factor: 10.864
Authors: Michael B Wallace; Jorge M S Pascual; Massimo Raimondo; Timothy A Woodward; Barbara L McComb; Julia E Crook; Margaret M Johnson; Mohammad A Al-Haddad; Seth A Gross; Surakit Pungpapong; Joy N Hardee; John A Odell Journal: JAMA Date: 2008-02-06 Impact factor: 56.272
Authors: Annette Fritscher-Ravens; Bruce L Davidson; Hans-Peter Hauber; Karl H Bohuslavizki; Christoph Bobrowski; Christian Lund; Wolfram Trudo Knöfel; Nib Soehendra; Lars Brandt; Margaret S Pepe; Almuth Pforte Journal: Am J Respir Crit Care Med Date: 2003-08-06 Impact factor: 21.405