F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage.

Two female patients aged 62 and 74 years underwent F-18 FDG PET/CT for evaluation of a large hepatic tumor. Subsequently, both patients underwent a partial hepatectomy which histopathologically revealed benign hepatic angiomyolipomas (AMLs). One patient with AML with a massive intratumoral hemorrhage presented with multiple foci demonstrating an increased FDG uptake along the margin of the cold defects that corresponded to low density areas within the tumor on contrast-enhanced CT, whereas the other patient with AML without any hemorrhage presented with a low FDG uptake in the tumor. This report demonstrates that benign hepatic AMLs may demonstrate increased FDG uptake if there is hemorrhage and a related inflammatory response.