Literature DB >> 20025356

Mental health problems in adults with Williams syndrome.

Chris Stinton1, Sarah Elison, Patricia Howlin.   

Abstract

Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities-PAS-ADD (Moss, Goldberg, et al., 1996). Factors potentially associated with mental health problems were also explored. The PAS-ADD identified mental health problems in 24% of the sample. The most common were anxiety (16.5%) and specific phobias (12%). Other diagnoses included depression, agoraphobia, and social phobia. No association was found between the presence of mental health problems and either individual (e.g., age, IQ, language level) or external (life events) variables.

Entities:  

Mesh:

Year:  2010        PMID: 20025356     DOI: 10.1352/1944-7558-115.1.3

Source DB:  PubMed          Journal:  Am J Intellect Dev Disabil        ISSN: 1944-7558


  21 in total

1.  White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome.

Authors:  Suzanne N Avery; Tricia A Thornton-Wells; Adam W Anderson; Jennifer Urbano Blackford
Journal:  Neuroimage       Date:  2011-10-08       Impact factor: 6.556

2.  Children with 7q11.23 duplication syndrome: psychological characteristics.

Authors:  Carolyn B Mervis; Bonita P Klein-Tasman; Myra J Huffman; Shelley L Velleman; C Holley Pitts; Danielle R Henderson; Janet Woodruff-Borden; Colleen A Morris; Lucy R Osborne
Journal:  Am J Med Genet A       Date:  2015-04-21       Impact factor: 2.802

3.  LIMK1 regulates long-term memory and synaptic plasticity via the transcriptional factor CREB.

Authors:  Zarko Todorovski; Suhail Asrar; Jackie Liu; Ner Mu Nar Saw; Krutika Joshi; Miguel A Cortez; O Carter Snead; Wei Xie; Zhengping Jia
Journal:  Mol Cell Biol       Date:  2015-02-02       Impact factor: 4.272

Review 4.  Copy number variants at Williams-Beuren syndrome 7q11.23 region.

Authors:  Giuseppe Merla; Nicola Brunetti-Pierri; Lucia Micale; Carmela Fusco
Journal:  Hum Genet       Date:  2010-05-01       Impact factor: 4.132

5.  Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome: A Case Series.

Authors:  Francisca Valdes; Christopher J Keary; Jennifer E Mullett; Michelle L Palumbo; Jessica L Waxler; Barbara R Pober; Christopher J McDougle
Journal:  J Autism Dev Disord       Date:  2018-03

6.  The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development.

Authors:  Andrew T N Tebbenkamp; Luis Varela; Jinmyung Choi; Miguel I Paredes; Alice M Giani; Jae Eun Song; Matija Sestan-Pesa; Daniel Franjic; André M M Sousa; Zhong-Wu Liu; Mingfeng Li; Candace Bichsel; Marco Koch; Klara Szigeti-Buck; Fuchen Liu; Zhuo Li; Yuka I Kawasawa; Constantinos D Paspalas; Yann S Mineur; Paolo Prontera; Giuseppe Merla; Marina R Picciotto; Amy F T Arnsten; Tamas L Horvath; Nenad Sestan
Journal:  Cell       Date:  2018-11-01       Impact factor: 41.582

7.  Longitudinal course of anxiety in children and adolescents with Williams syndrome.

Authors:  Janet Woodruff-Borden; Doris J Kistler; Danielle R Henderson; Nicole A Crawford; Carolyn B Mervis
Journal:  Am J Med Genet C Semin Med Genet       Date:  2010-05-15       Impact factor: 3.908

8.  Genetic counseling of adults with Williams syndrome: a first study.

Authors:  Katrina Farwig; Amanda G Harmon; Kristina M Fontana; Carolyn B Mervis; Colleen A Morris
Journal:  Am J Med Genet C Semin Med Genet       Date:  2010-05-15       Impact factor: 3.908

9.  Regionally specific increased volume of the amygdala in Williams syndrome: evidence from surface-based modeling.

Authors:  Brian W Haas; Kristen Sheau; Ryan G Kelley; Paul M Thompson; Allan L Reiss
Journal:  Hum Brain Mapp       Date:  2012-11-14       Impact factor: 5.038

10.  The interplay between anxiety and social functioning in Williams syndrome.

Authors:  Deborah M Riby; Mary Hanley; Hannah Kirk; Fiona Clark; Katie Little; Ruth Fleck; Emily Janes; Linzi Kelso; Fionnuala O'Kane; Rachel Cole-Fletcher; Marianne Hvistendahl Allday; Darren Hocking; Kim Cornish; Jacqui Rodgers
Journal:  J Autism Dev Disord       Date:  2014-05
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