Literature DB >> 20025237

N-Heterocyclic carbene-catalyzed intramolecular aldehyde-nitrile cross coupling: an easy access to 3- aminochromones.

Seenuvasan Vedachalam1, Jing Zeng, Bala Kishan Gorityala, Meraldo Antonio, Xue-Wei Liu.   

Abstract

An immense effort has been made to develop an efficient strategy for the carbon-carbon bond formation between aldehyde and nitrile intramolecularly using an N-heterocyclic carbene catalyst to derive 3-aminochromone derivatives in good to excellent yields (80-95%).

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Year:  2010        PMID: 20025237     DOI: 10.1021/ol9026232

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Investigation of Direct and Retro Chromone-2-Carboxamides Based Analogs of Pseudomonas aeruginosa Quorum Sensing Signal as New Anti-Biofilm Agents.

Authors:  Jeanne Trognon; Gonzalo Vera; Maya Rima; Jean-Luc Stigliani; Laurent Amielet; Salomé El Hage; Barbora Lajoie; Christine Roques; Fatima El Garah
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-29
  1 in total

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