Literature DB >> 20024057

A low power, on demand electrothermal valve for wireless drug delivery applications.

Po-Ying Li1, Tina K Givrad, Roya Sheybani, Daniel P Holschneider, Jean-Michel I Maarek, Ellis Meng.   

Abstract

We present a low power, on demand Parylene MEMS electrothermal valve. A novel Omega-shaped thermal resistive element requires low power (approximately mW) and enables rapid valve opening (approximately ms). Using both finite element analysis and valve opening experiments, a robust resistive element design for improved valve opening performance in water was obtained. In addition, a thermistor, as an inrush current limiter, was added into the valve circuit to provide variable current ramping. Wireless activation of the valve using RF inductive power transfer was demonstrated.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 20024057      PMCID: PMC4134919          DOI: 10.1039/b910248e

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  6 in total

1.  Functional hydrogel structures for autonomous flow control inside microfluidic channels

Authors: 
Journal:  Nature       Date:  2000-04-06       Impact factor: 49.962

2.  An implantable bolus infusion pump for use in freely moving, nontethered rats.

Authors:  D P Holschneider; J-M I Maarek; J Harimoto; J Yang; O U Scremin
Journal:  Am J Physiol Heart Circ Physiol       Date:  2002-06-20       Impact factor: 4.733

3.  Expandable microspheres for the handling of liquids.

Authors:  Patrick Griss; Helene Andersson; Göran Stemme
Journal:  Lab Chip       Date:  2002-02-27       Impact factor: 6.799

4.  Electrothermally activated microchips for implantable drug delivery and biosensing.

Authors:  John M Maloney; Scott A Uhland; Benjamin F Polito; Norman F Sheppard; Christina M Pelta; John T Santini
Journal:  J Control Release       Date:  2005-11-08       Impact factor: 9.776

Review 5.  Brain maps on the go: functional imaging during motor challenge in animals.

Authors:  D P Holschneider; J-M I Maarek
Journal:  Methods       Date:  2008-06-11       Impact factor: 3.608

6.  Transcutaneous RF-powered implantable minipump driven by a class-E transmitter.

Authors:  William H Moore; Daniel P Holschneider; Tina K Givrad; Jean-Michel I Maarek
Journal:  IEEE Trans Biomed Eng       Date:  2006-08       Impact factor: 4.538

  6 in total
  2 in total

Review 1.  Micro- and nano-fabricated implantable drug-delivery systems.

Authors:  Ellis Meng; Tuan Hoang
Journal:  Ther Deliv       Date:  2012-12

Review 2.  MEMS-enabled implantable drug infusion pumps for laboratory animal research, preclinical, and clinical applications.

Authors:  Ellis Meng; Tuan Hoang
Journal:  Adv Drug Deliv Rev       Date:  2012-08-19       Impact factor: 15.470

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.