Literature DB >> 20023836

Responsive magnetic resonance imaging contrast agents as chemical sensors for metals in biology and medicine.

Emily L Que1, Christopher J Chang.   

Abstract

This tutorial review highlights progress in the development of responsive magnetic resonance imaging (MRI) contrast agents for detecting and sensing biologically relevant metal ions. Molecular imaging with bioactivatable MRI indicators offers a potentially powerful methodology for studying the physiology and pathology of metals by capturing dynamic three-dimensional images of living systems for research and clinical applications. This emerging area at the interface of inorganic chemistry and the life sciences offers a broad palette of opportunities for researchers with interests ranging from coordination chemistry and spectroscopy to supramolecular chemistry and molecular recognition to metals in biology and medicine.

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Year:  2009        PMID： 20023836     DOI： 10.1039/b914348n

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  46 in total

1.  Label-free catalytic and molecular beacon containing an abasic site for sensitive fluorescent detection of small inorganic and organic molecules.

Authors:  Panshu Song; Yu Xiang; Hang Xing; Zhaojuan Zhou; Aijun Tong; Yi Lu
Journal:  Anal Chem       Date:  2012-03-07       Impact factor: 6.986

2.  In vivo characterization of a smart MRI agent that displays an inverse response to calcium concentration.

Authors:  Ilgar Mamedov; Santiago Canals; Jörg Henig; Michael Beyerlein; Yusuke Murayama; Hermann A Mayer; Nikos K Logothetis; Goran Angelovski
Journal:  ACS Chem Neurosci       Date:  2010-10-20       Impact factor: 4.418

Review 3.  MRI biosensors: a short primer.

Authors:  Angelique Louie
Journal:  J Magn Reson Imaging       Date:  2013-09       Impact factor: 4.813

Review 4.  Lanthanide probes for bioresponsive imaging.

Authors:  Marie C Heffern; Lauren M Matosziuk; Thomas J Meade
Journal:  Chem Rev       Date:  2013-12-13       Impact factor: 60.622

Review 5.  Basic MR relaxation mechanisms and contrast agent design.

Authors:  Luis M De León-Rodríguez; André F Martins; Marco C Pinho; Neil M Rofsky; A Dean Sherry
Journal:  J Magn Reson Imaging       Date:  2015-05-14       Impact factor: 4.813

6.  A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model.

Authors:  Emily L Que; Elizabeth J New; Christopher J Chang
Journal:  Chem Sci       Date:  2012-04-18       Impact factor: 9.825

7.  Aqueous Lanthanide Chemistry in Asymmetric Catalysis and Magnetic Resonance Imaging.

Authors:  Matthew J Allen
Journal:  Synlett       Date:  2016-06       Impact factor: 2.454

8.  Modulating water-exchange rates of lanthanide(III)-containing polyaminopolycarboxylate-type complexes using polyethylene glycol.

Authors:  Buddhima N Siriwardena-Mahanama; Matthew J Allen
Journal:  Dalton Trans       Date:  2013-05-21       Impact factor: 4.390

Review 9.  Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.

Authors:  Jessica Wahsner; Eric M Gale; Aurora Rodríguez-Rodríguez; Peter Caravan
Journal:  Chem Rev       Date:  2018-10-16       Impact factor: 60.622

10.  Conjugation to Biocompatible Dendrimers Increases Lanthanide T2 Relaxivity of Hydroxypyridinone (HOPO) Complexes for Magnetic Resonance Imaging (MRI).

Authors:  Piper J Klemm; William C Floyd; Christopher M Andolina; Jean M J Fréchet; Kenneth N Raymond
Journal:  Eur J Inorg Chem       Date:  2012-04       Impact factor: 2.524
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