Literature DB >> 20023718

Global signatures of protein and mRNA expression levels.

Raquel de Sousa Abreu1, Luiz O Penalva, Edward M Marcotte, Christine Vogel.   

Abstract

Cellular states are determined by differential expression of the cell's proteins. The relationship between protein and mRNA expression levels informs about the combined outcomes of translation and protein degradation which are, in addition to transcription and mRNA stability, essential contributors to gene expression regulation. This review summarizes the state of knowledge about large-scale measurements of absolute protein and mRNA expression levels, and the degree of correlation between the two parameters. We summarize the information that can be derived from comparison of protein and mRNA expression levels and discuss how corresponding sequence characteristics suggest modes of regulation.

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Year:  2009        PMID： 20023718      PMCID： PMC4089977          DOI： 10.1039/b908315d

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  190 in total

1.  Regulation of noise in the expression of a single gene.

Authors:  Ertugrul M Ozbudak; Mukund Thattai; Iren Kurtser; Alan D Grossman; Alexander van Oudenaarden
Journal:  Nat Genet       Date:  2002-04-22       Impact factor: 38.330

2.  Gene expression analyzed by high-resolution state array analysis and quantitative proteomics: response of yeast to mating pheromone.

Authors:  Vivian L MacKay; Xiaohong Li; Mark R Flory; Eileen Turcott; G Lynn Law; Kyle A Serikawa; X L Xu; Hookeun Lee; David R Goodlett; Ruedi Aebersold; Lue Ping Zhao; David R Morris
Journal:  Mol Cell Proteomics       Date:  2004-02-06       Impact factor: 5.911

3.  Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes.

Authors:  Arvind Raghavan; Rachel L Ogilvie; Cavan Reilly; Michelle L Abelson; Shalini Raghavan; Jayprakash Vasdewani; Mitchell Krathwohl; Paul R Bohjanen
Journal:  Nucleic Acids Res       Date:  2002-12-15       Impact factor: 16.971

Review 4.  Regulation of translation via mRNA structure in prokaryotes and eukaryotes.

Authors:  Marilyn Kozak
Journal:  Gene       Date:  2005-10-05       Impact factor: 3.688

5.  TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha.

Authors:  M Piecyk; S Wax; A R Beck; N Kedersha; M Gupta; B Maritim; S Chen; C Gueydan; V Kruys; M Streuli; P Anderson
Journal:  EMBO J       Date:  2000-08-01       Impact factor: 11.598

6.  Biotinylated tags for recovery and characterization of ribonucleoprotein complexes.

Authors:  Luiz O F Penalva; Jack D Keene
Journal:  Biotechniques       Date:  2004-10       Impact factor: 1.993

7.  The ubiquitin-proteasome pathway and enhanced activity of NF-kappaB in gastric carcinoma.

Authors:  Lingfei Wu; Zejin Pu; Jialin Feng; Guoping Li; Zhichao Zheng; Wenlv Shen
Journal:  J Surg Oncol       Date:  2008-04-01       Impact factor: 3.454

8.  Thrombopoietin production is inhibited by a translational mechanism.

Authors:  N Ghilardi; A Wiestner; R C Skoda
Journal:  Blood       Date:  1998-12-01       Impact factor: 22.113

9.  Structural disorder serves as a weak signal for intracellular protein degradation.

Authors:  P Tompa; J Prilusky; I Silman; J L Sussman
Journal:  Proteins       Date:  2008-05-01

10.  Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling.

Authors:  Nicholas T Ingolia; Sina Ghaemmaghami; John R S Newman; Jonathan S Weissman
Journal:  Science       Date:  2009-02-12       Impact factor: 47.728
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  460 in total

1.  VEGF and VEGFR1 levels in different regions of the normal and preeclampsia placentae.

Authors:  Akriti S Sahay; Anjali T Jadhav; Deepali P Sundrani; Girija N Wagh; Savita S Mehendale; Preeti Chavan-Gautam; Sadhana R Joshi
Journal:  Mol Cell Biochem       Date:  2017-08-02       Impact factor: 3.396

2.  Commercially available antibodies against human and murine histamine H₄-receptor lack specificity.

Authors:  Silke Beermann; Roland Seifert; Detlef Neumann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-11-10       Impact factor: 3.000

3.  Known and novel post-transcriptional regulatory sequences are conserved across plant families.

Authors:  Justin N Vaughn; Sally R Ellingson; Flavio Mignone; Albrecht von Arnim
Journal:  RNA       Date:  2012-01-11       Impact factor: 4.942

4.  Protein turnover quantification in a multilabeling approach: from data calculation to evaluation.

Authors:  Christian Trötschel; Stefan P Albaum; Daniel Wolff; Simon Schröder; Alexander Goesmann; Tim W Nattkemper; Ansgar Poetsch
Journal:  Mol Cell Proteomics       Date:  2012-04-06       Impact factor: 5.911

5.  Estrogen coordinates translation and transcription, revealing a role for NRSF in human breast cancer cells.

Authors:  Michael W Bronson; Sara Hillenmeyer; Richard W Park; Alexander S Brodsky
Journal:  Mol Endocrinol       Date:  2010-04-14

Review 6.  Systems biology in immunology: a computational modeling perspective.

Authors:  Ronald N Germain; Martin Meier-Schellersheim; Aleksandra Nita-Lazar; Iain D C Fraser
Journal:  Annu Rev Immunol       Date:  2011       Impact factor: 28.527

7.  Molecular characterization and expression of suppressor of cytokine signaling (SOCS) 1, 2 and 3 under acute hypoxia and reoxygenation in pufferfish, Takifugu fasciatus.

Authors:  Dan Wang; Xin Wen; Xinyu Zhang; Yadong Hu; Xinru Li; Wenxu Zhu; Tao Wang; Shaowu Yin
Journal:  Genes Genomics       Date:  2018-07-23       Impact factor: 1.839

8.  Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel.

Authors:  Cen Li; Soyoung Park; Xiaowen Zhang; Wei Dai; Dazhong Xu
Journal:  J Biol Chem       Date:  2017-05-17       Impact factor: 5.157

9.  Matrix metalloproteinase expression is altered in the small and large intestine following fractionated radiation in vivo.

Authors:  Romany L Stansborough; Noor Al-Dasooqi; Emma H Bateman; Joanne M Bowen; Dorothy M K Keefe; Richard M Logan; Ann S J Yeoh; Eric E K Yeoh; Andrea M Stringer; Rachel J Gibson
Journal:  Support Care Cancer       Date:  2018-05-12       Impact factor: 3.603

10.  Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury.

Authors:  Jin Huang; Danyang Wan; Jianshuang Li; Hong Chen; Kun Huang; Ling Zheng
Journal:  Epigenetics       Date:  2015-01-20       Impact factor: 4.528
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