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Literature DB >> 20023678

Intraperitoneal catheter placement for pharmacological imaging studies in conscious mice.

Eilis Boudreau¹, Gang Chen, Xin Li, Kari Buck, Robert Hitzemann, Debra Hickman.

Abstract

Imaging studies that use rodents sometimes involve intraperitoneal administration of pharmacological compounds. To facilitate such studies, the authors developed a simple and easily mastered technique for placing an intraperitoneal catheter in a conscious mouse. This technique eliminates the need to remove the animal from the scanner to administer a drug through the intraperitoneal route.

Entities: Chemical Disease Gene Species

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Year: 2010 PMID： 20023678 PMCID： PMC4994513 DOI： 10.1038/laban0110-23

Source DB: PubMed Journal: Lab Anim (NY) ISSN： 0093-7355 Impact factor: 12.625

13 in total

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Authors: Jean A King; Timothy S Garelick; Mathew E Brevard; Wei Chen; Tara L Messenger; Timothy Q Duong; Craig F Ferris
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3. Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration.

Authors: Ikuhiro Kida; Douglas L Rothman; Fahmeed Hyder
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3. The Triple Combination Phentermine Plus 5-HTP/Carbidopa Leads to Greater Weight Loss, With Fewer Psychomotor Side Effects Than Each Drug Alone.

Authors: Claudia I Perez; B Kalyanasundar; Mario G Moreno; Ranier Gutierrez
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3 in total

Intraperitoneal catheter placement for pharmacological imaging studies in conscious mice.

1. Ethics and animal welfare related to in vivo pharmacology and toxicology in laboratory animals.

2. Procedure for minimizing stress for fMRI studies in conscious rats.

3. Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration.

4. Pharmacological MRI in awake rats predicts selective binding of alpha4beta2 nicotinic receptors.

5. Errors related to different techniques of intraperitoneal injection in mice.

6. Intraperitoneal injection of mice.

7. In vivo auditory brain mapping in mice with Mn-enhanced MRI.

8. Optimizing experimental protocols for quantitative behavioral imaging with 18F-FDG in rodents.

9. Validation of cerebral blood perfusion imaging as a modality for quantitative pharmacological MRI in rats.

10. Intraperitoneal administration and other modifications of the 2-deoxy-D-glucose technique.

1. Electrochemical detection of exogenously administered melatonin in the brain.

2. Novel intrathecal and subcutaneous catheter delivery systems in the mouse.

3. The Triple Combination Phentermine Plus 5-HTP/Carbidopa Leads to Greater Weight Loss, With Fewer Psychomotor Side Effects Than Each Drug Alone.