Literature DB >> 20022857

Norovirus and Rotavirus--two major causative agents of sporadic viral gastroenteritis in hospitalized Polish children.

E Oldak1, A Sulik, D Rozkiewicz, N Liwoch-Nienartowicz, E Zawadzka.   

Abstract

PURPOSE: The aim of the study was to establish the main etiologic agents of acute viral gastroenteritis and to asses the severity of illness associated with the different viral agents of gastroenteritis in children hospitalized during spring/summer season 2008.
MATERIAL AND METHODS: 181 stool specimens were collected from children under 5 years of age, hospitalized with acute viral diarrhea from April to September 2008. Commercial enzyme immunoassay kits were used to detect noroviruses. The immunochromatographic tests for combined detection of rotaviruses and adenoviruses were performed routinely in our department in all in-patients suspected for viral gastroenteritis.
RESULTS: A viral etiologic agents were detected in 108 of 181 (59.7%) samples tested. Dual viral pathogens (rotavirus and norovirus) were found in 3 of 181 (1.7%) samples. Rotavirus was the most common viral pathogen found in the study group (86/181; 47.5%), followed by NV (19/181; 10.5%) and adenoviruses (3/181; 1.7%). Approximately, 60% of acute gastroenteritis episodes occurring in children less than 5 years of age were accounted for by infection due to rotavirus and/or norovirus. Norovirus cases were clinically indistinguishable from those of rotavirus origin in children aged less than 2 years whereas they were slightly milder in older group of patients.
CONCLUSIONS: Rotavirus infections are leading cause of children's hospitalization in spring months whereas Norovirus infections during spring/summer time. There is a great need to apply molecular diagnostic tools to determine the actual and monitoring the changing etiology of acute enteritis in Polish population.

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Year:  2009        PMID: 20022857     DOI: 10.2478/v10039-009-0046-z

Source DB:  PubMed          Journal:  Adv Med Sci        ISSN: 1896-1126            Impact factor:   3.287


  4 in total

1.  Simultaneous detection of seven enteric viruses associated with acute gastroenteritis by a multiplexed Luminex-based assay.

Authors:  Yan Liu; Zi-qian Xu; Qing Zhang; Miao Jin; Jie-mei Yu; Jin-song Li; Na Liu; Shu-xian Cui; Xiang-yu Kong; Hong Wang; Hui-ying Li; Wei-xia Cheng; Xue-jun Ma; Zhao-jun Duan
Journal:  J Clin Microbiol       Date:  2012-04-18       Impact factor: 5.948

2.  Clinical characteristics and outcome in norovirus gastroenteritis.

Authors:  Min-Sho Ku; Ji-Nan Sheu; Ching-Pin Lin; Yu-Hua Chao; Shan-Ming Chen
Journal:  Indian J Pediatr       Date:  2014-04-06       Impact factor: 1.967

3.  Norovirus infections in children under 5 years of age hospitalized due to the acute viral gastroenteritis in northeastern Poland.

Authors:  E Oldak; A Sulik; D Rozkiewicz; N Liwoch-Nienartowicz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-07-06       Impact factor: 3.267

4.  Clinical characteristics and molecular epidemiology of noroviruses in outpatient children with acute gastroenteritis in Huzhou of China.

Authors:  Weihua Zou; Dawei Cui; Xiang Wang; Huihui Guo; Xing Yao; Miao Jin; Qiuling Huang; Min Gao; Xiaohong Wen
Journal:  PLoS One       Date:  2015-05-26       Impact factor: 3.240

  4 in total

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