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Literature DB >> 20022233

Transmitting the message: intracellular mRNA localization.

Abstract

The intracellular localization of mRNA is an important mechanism for targeting proteins to their sites of function. Localized transcripts play key roles ranging from body axis determination to synapse plasticity, and recent studies highlight how common localized transcripts are in a variety of model organisms. In this review, we consider the full range of known mechanisms for delivering transcripts and anchoring them at their site of function. Finally, we evaluate the progress that has been made in the nervous system in understanding the mechanism and function of mRNA localization and translation regulation. Copyright 2009 Elsevier Ltd. All rights reserved.

Mesh：

Substances：
RNA, Messenger

Year: 2010 PMID： 20022233 DOI： 10.1016/j.ceb.2009.11.011

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

38 in total

1. hsp70 mRNA temporal localization in rat skeletal myofibers and blood vessels post-exercise.

Authors: Jordan Thomas Silver; Hana Kowalchuk; Earl G Noble
Journal: Cell Stress Chaperones Date: 2011-09-28 Impact factor: 3.667

Review 2. Synaptic control of local translation: the plot thickens with new characters.

Authors: María Gabriela Thomas; Malena Lucía Pascual; Darío Maschi; Luciana Luchelli; Graciela Lidia Boccaccio
Journal: Cell Mol Life Sci Date: 2013-11-10 Impact factor: 9.261

3. An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho-GTP.

Authors: Guoning Liao; Xinghong Ma; Gang Liu
Journal: J Cell Sci Date: 2011-01-25 Impact factor: 5.285

10. Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1.

Authors: Noga Gershoni-Emek; Arnon Mazza; Michael Chein; Tal Gradus-Pery; Xin Xiang; Ka Wan Li; Roded Sharan; Eran Perlson
Journal: Mol Cell Proteomics Date: 2015-11-23 Impact factor: 5.911

Transmitting the message: intracellular mRNA localization.

1. hsp70 mRNA temporal localization in rat skeletal myofibers and blood vessels post-exercise.

Review 2. Synaptic control of local translation: the plot thickens with new characters.

3. An RNA-zipcode-independent mechanism that localizes Dia1 mRNA to the perinuclear ER through interactions between Dia1 nascent peptide and Rho-GTP.

Review 4. Mechanisms of dendritic mRNA transport and its role in synaptic tagging.

Review 5. Control of cell migration through mRNA localization and local translation.

Review 6. Yeast studies reveal moonlighting functions of the ancient actin cytoskeleton.

7. Cotranslational transport of ABP140 mRNA to the distal pole of S. cerevisiae.

8. ParticleStats: open source software for the analysis of particle motility and cytoskeletal polarity.

9. Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization.

10. Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1.