Literature DB >> 20020733

Stereoselective aldol reaction of glutarimides using pseudo C(2) symmetry.

Yohsuke Watanabe1, Takashi Yamazaki, Toshio Kubota.   

Abstract

The boron aldol reaction of beta-substituted glutaric imides bearing an oxazolidinone-based auxiliary proceeds with excellent diastereoselectivity; switching the tertiary amine employed between i-Pr(2)EtN or Et(3)N affords enantiomeric lactone product.

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Year:  2010        PMID: 20020733     DOI: 10.1021/ol902592t

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Diastereoselective Mannich reactions of pseudo-C2-symmetric glutarimide with activated imines.

Authors:  Tatsuya Ishikawa; Tomoko Kawasaki-Takasuka; Toshio Kubota; Takashi Yamazaki
Journal:  Beilstein J Org Chem       Date:  2017-11-21       Impact factor: 2.883

  1 in total

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