Literature DB >> 20019696

A piece in the puzzle of personalized medicine.

H K Kroemer1, H E Meyer zu Schwabedissen.   

Abstract

Predicting individual drug response based on inherited factors remains a major challenge. Some examples of significant contributions of single genetic variants to overall therapeutic success of drugs in complex diseases are currently emerging. For most compounds, however, multiple genetic and nongenetic factors will modify drug action. Comprehensive integration of these factors will determine the role of pharmacogenomics for personalized medicine.

Mesh：

Year:  2010        PMID： 20019696     DOI： 10.1038/clpt.2009.219

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  3 in total

Review 1.  Pharmacogenomics: will the promise be fulfilled?

Authors:  Russ B Altman; Heyo K Kroemer; Catherine A McCarty; Mark J Ratain; Dan Roden
Journal:  Nat Rev Genet       Date:  2010-11-30       Impact factor: 53.242

2.  Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C > T variants: a case report.

Authors:  Henriette E Meyer zu Schwabedissen; Werner Siegmund; Heyo K Kroemer; Jens D Rollnik
Journal:  BMC Res Notes       Date:  2014-10-03

Review 3.  HLA-associated adverse drug reactions - scoping review.

Authors:  Chiara Jeiziner; Ursina Wernli; Katja Suter; Kurt E Hersberger; Henriette E Meyer Zu Schwabedissen
Journal:  Clin Transl Sci       Date:  2021-06-09       Impact factor: 4.689
  3 in total

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