| Literature DB >> 20017402 |
G V Karpova, T I Fomina, T V Vetoshkina, T Iu Dubskaia, L A Ermolaeva, A A Churin.
Abstract
The influence of various antineoplastic preparations (farmorubicin, paclitaxel, etoposide, platidiam) on morphological and functional status of the liver in experimental animals was studied. It is shown, that all these antineoplastic drugs possess strong hepatotoxic activity and thereby cause toxic hepatitis and increase activity of hepatic enzymes. Biochemical parameters were normalized within 30 days after treatment whereas morphological changes persisted somewhat longer.Entities:
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Year: 2009 PMID： 20017402
Source DB: PubMed Journal: Vestn Ross Akad Med Nauk ISSN： 0869-6047