Literature DB >> 200169

Lysosomal enzymes in human lymphoblastoid lines: unusual characteristics of RAJI and DAUDI.

D M Swallow, S E Gardiner, H Harris, E Arthur, C M Steel, H J Evans.   

Abstract

The lysosomal enzymes N-acetyl hexosaminidase, alpha-galactosidase and alpha-mannosidase vary in electrophoretic mobility in different human lymphoblastoid (lymphoid) lines. The relative mobilities of these three enzymes and three out of four other lysosomal enzymes tested correlate well with each other. The patterns appear to be relatively stable characteristics of each line. The lines RAJI and DAUDI show a strikingly fast electrophoretic mobility for all of these enzymes. N-acetyl hexosaminidase is also markedly deficient in DAUDI.

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Year:  1977        PMID: 200169     DOI: 10.1111/j.1469-1809.1977.tb01957.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  3 in total

1.  An enzyme with properties similar to those of beta-N-acetylhexosaminidase S is expressed in the promyelocytic cell line HL-60.

Authors:  C Emiliani; T Beccari; A Tabilio; A Orlacchio; R Hosseini; J L Stirling
Journal:  Biochem J       Date:  1990-04-01       Impact factor: 3.857

2.  Treatment of HL-60 cells with dimethyl sulphoxide inhibits the formation of beta-N-acetylhexosaminidase S.

Authors:  C Emiliani; F Falzetti; A Orlacchio; J L Stirling
Journal:  Biochem J       Date:  1990-11-15       Impact factor: 3.857

3.  NADH cytochrome b5 reductase activity in lymphoid cell lines. Expression of the defect in epstein Barr virus transformed lymphoblastoid cell lines from patients with recessive congenital methemoglobinemia.

Authors:  D Lostanlen; G Lenoir; J C Kaplan
Journal:  J Clin Invest       Date:  1981-07       Impact factor: 14.808

  3 in total

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