| Literature DB >> 20014771 |
Claude Larrivée-Aboussafy1, Brian P Jones, Kristin E Price, Mark A Hardink, Robert W McLaughlin, Brett M Lillie, Joel M Hawkins, Rajappa Vaidyanathan.
Abstract
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been found to catalyze the amidation of acyl imidazoles. The rate acceleration is especially evident with traditionally unreactive, electron-deficient anilines. DBU is readily available and offers safety and cost advantages over more commonly employed catalysts such as 1-hydroxybenzotriazole.Entities:
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Year: 2010 PMID： 20014771 DOI： 10.1021/ol9026599
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005