BACKGROUND: A practical, easy to use model was developed to stratify risk groups in surgical patients: the Identification of Risk In Surgical patients (IRIS) score. METHODS: Over 15 years an extensive database was constructed in a general surgery unit, containing all patients who underwent general or trauma surgery. A logistic regression model was developed to predict mortality. This model was simplified to the IRIS score to enhance practicality. Receiver operating characteristic (ROC) curve analysis was performed. RESULTS: The database contained a consecutive series of 33 224 patients undergoing surgery. Logistic regression analysis gave the following formula for the probability of mortality: P (mortality) = A/(1 + A), where A = exp (-4.58 + (0.26 x acute admission) + (0.63 x acute operation) + (0.044 x age) + (0.34 x severity of surgery)). The area under the ROC curve (AUC) was 0.92. The IRIS score also included age (divided into quartiles, 0-3 points), acute admission, acute operation and grade of surgery. The AUC predicting postoperative mortality was 0.90. CONCLUSION: The IRIS score accurately predicted mortality after general or trauma surgery. Copyright 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
BACKGROUND: A practical, easy to use model was developed to stratify risk groups in surgical patients: the Identification of Risk In Surgical patients (IRIS) score. METHODS: Over 15 years an extensive database was constructed in a general surgery unit, containing all patients who underwent general or trauma surgery. A logistic regression model was developed to predict mortality. This model was simplified to the IRIS score to enhance practicality. Receiver operating characteristic (ROC) curve analysis was performed. RESULTS: The database contained a consecutive series of 33 224 patients undergoing surgery. Logistic regression analysis gave the following formula for the probability of mortality: P (mortality) = A/(1 + A), where A = exp (-4.58 + (0.26 x acute admission) + (0.63 x acute operation) + (0.044 x age) + (0.34 x severity of surgery)). The area under the ROC curve (AUC) was 0.92. The IRIS score also included age (divided into quartiles, 0-3 points), acute admission, acute operation and grade of surgery. The AUC predicting postoperative mortality was 0.90. CONCLUSION: The IRIS score accurately predicted mortality after general or trauma surgery. Copyright 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Authors: Frederik J van der Sluis; Cornelis Slagt; Barbara Liebman; Jan Beute; Jan W R Mulder; Alexander F Engel Journal: BMC Surg Date: 2011-08-23 Impact factor: 2.102