| Literature DB >> 20013573 |
Kosmas Sarafidis1, Elias Iosifidis, Evangelos Gikas, Maria Tsivitanidou, Vassiliki Drossou-Agakidou, Emmanuel Roilides.
Abstract
We present a case of successfully treated persistent bacteremia due to Gram-positive bacteria with daptomycin in a preterm neonate. Daptomycin was given at higher doses (6 mg/kg/dose) and shorter intervals (every 12 hours) than those recommended for adults with no adverse events. Peak and trough serum concentrations of daptomycin were 27.3 and 11.6 μg/mL [DOSAGE ERROR CORRECTED] at day 4 as well as 22.9 and 7.9 μg/mL [DOSAGE ERROR CORRECTED]at day 11 after initiation of treatment, respectively. Copyright Thieme Medical Publishers.Entities:
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Year: 2009 PMID: 20013573 DOI: 10.1055/s-0029-1243370
Source DB: PubMed Journal: Am J Perinatol ISSN: 0735-1631 Impact factor: 1.862