Literature DB >> 20013270

Non-Hodgkin's lymphoma following treatment with etanercept in ankylosing spondylitis.

Kenan Aksu1, Seckin Cagirgan, Nazan Ozsan, Gokhan Keser, Fahri Sahin.   

Abstract

Anti-TNF drugs may increase lymphoma risk in autoimmune rheumatic diseases, such as rheumatoid arthritis, but there have been no reports stating increased risk of lymphoma in ankylosing spondylitis (AS). Before 2 years, we had presented a case with AS developing Hodgkin's lymphoma following 6 months of etanercept treatment. Hereby, we present another case with AS developing non-Hodgkin's lymphoma (NHL), subsequent to 11 months of etanercept treatment. Pathological analysis revealed diffuse large B cell NHL. Although this is a report of a single case, cautious use of anti-TNF drugs is strongly recommended as they might cause lymphoma development even in AS.

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Year:  2009        PMID: 20013270     DOI: 10.1007/s00296-009-1265-0

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  10 in total

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  5 in total

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