| Literature DB >> 20013145 |
Thomas Skripuletz1, Refik Pul, Julian Herrmann, Eva Bueltmann, Ulrich Wurster, Martin Stangel, Corinna Trebst.
Abstract
We report herein a clinical case of a patient with meningeal carcinomatosis from penile squamous cell carcinoma. A 68-year-old man presented with mental changes, headaches, and unstable gait. Examinations revealed brain metastases and infiltration of the leptomeninges and subarachnoid space by carcinoma cells. Only 11 months earlier the patient had been diagnosed with penile squamous cell carcinoma of poor differentiation and had underwent subtotal penectomy and adjuvant chemotherapy and radiation. Infiltration of the central nervous system with penile cancer is extremely rare, and only five cases with brain metastases have been described to date. This is the first report of a patient with penile cancer spread to the leptomeninges.Entities:
Mesh:
Year: 2009 PMID: 20013145 DOI: 10.1007/s11060-009-0087-y
Source DB: PubMed Journal: J Neurooncol ISSN: 0167-594X Impact factor: 4.130