| Literature DB >> 20011306 |
W Donald Buie1, Jo-Anne P Attard.
Abstract
Recent evidence suggests that intensive follow-up after curative resection of colorectal cancer is associated with a small but significant improvement in survival. Regimens that employ cross-sectional imaging and carcinoembryonic antigen determination appear to have the greatest benefit. A risk-adapted approach to follow-up, intensively following patients at highest risk of recurrence, increases efficacy and cost-effectiveness. Ongoing improvements in risk stratification, disease detection, and treatment will increase the benefits of postoperative surveillance. Large randomized controlled trials are needed to determine the optimal surveillance regimen and must include an analysis of survival, quality of life, and cost-effectiveness to assess efficacy properly.Entities:
Keywords: Colorectal neoplasm; follow-up; neoplasm metastasis/diagnosis; neoplasm recurrence/detection; surveillance; survival
Year: 2005 PMID: 20011306 PMCID: PMC2780095 DOI: 10.1055/s-2005-916284
Source DB: PubMed Journal: Clin Colon Rectal Surg ISSN: 1530-9681