Literature DB >> 20007989

Postoperative delirium and cognitive dysfunction.

S Deiner1, J H Silverstein.   

Abstract

Postoperative delirium and cognitive dysfunction (POCD) are topics of special importance in the geriatric surgical population. They are separate entities, whose relationship has yet to be fully elucidated. Although not limited to geriatric patients, the incidence and impact of both are more profound in geriatric patients. Delirium has been shown to be associated with longer and more costly hospital course and higher likelihood of death within 6 months or postoperative institutionalization. POCD has been associated with increased mortality, risk of leaving the labour market prematurely, and dependency on social transfer payments. Here, we review their definitions and aetiology, and discuss treatment and prevention in elderly patients undergoing major non-cardiac surgery. Good basic care demands identification of at-risk patients, awareness of common perioperative aggravating factors, simple prevention interventions, recognition of the disease states, and basic treatments for patients with severe hyperactive manifestations.

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Mesh:

Year:  2009        PMID: 20007989      PMCID: PMC2791855          DOI: 10.1093/bja/aep291

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  51 in total

1.  Test/re-test reliability of the CANTAB and ISPOCD neuropsychological batteries: theoretical and practical issues. Cambridge Neuropsychological Test Automated Battery. International Study of Post-Operative Cognitive Dysfunction.

Authors:  C Lowe; P Rabbitt
Journal:  Neuropsychologia       Date:  1998-09       Impact factor: 3.139

2.  Clarifying confusion: the confusion assessment method. A new method for detection of delirium.

Authors:  S K Inouye; C H van Dyck; C A Alessi; S Balkin; A P Siegal; R I Horwitz
Journal:  Ann Intern Med       Date:  1990-12-15       Impact factor: 25.391

3.  A multicomponent intervention to prevent delirium in hospitalized older patients.

Authors:  S K Inouye; S T Bogardus; P A Charpentier; L Leo-Summers; D Acampora; T R Holford; L M Cooney
Journal:  N Engl J Med       Date:  1999-03-04       Impact factor: 91.245

4.  Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats.

Authors:  Deborah J Culley; Mark G Baxter; Catherine A Crosby; Rustam Yukhananov; Gregory Crosby
Journal:  Anesth Analg       Date:  2004-11       Impact factor: 5.108

5.  Preoperative anxiety and emergence delirium and postoperative maladaptive behaviors.

Authors:  Zeev N Kain; Alison A Caldwell-Andrews; Inna Maranets; Brenda McClain; Dorothy Gaal; Linda C Mayes; Rui Feng; Heping Zhang
Journal:  Anesth Analg       Date:  2004-12       Impact factor: 5.108

6.  Do cognitive complaints either predict future cognitive decline or reflect past cognitive decline? A longitudinal study of an elderly community sample.

Authors:  A F Jorm; H Christensen; A E Korten; A S Henderson; P A Jacomb; A Mackinnon
Journal:  Psychol Med       Date:  1997-01       Impact factor: 7.723

7.  Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction.

Authors:  J T Moller; P Cluitmans; L S Rasmussen; P Houx; H Rasmussen; J Canet; P Rabbitt; J Jolles; K Larsen; C D Hanning; O Langeron; T Johnson; P M Lauven; P A Kristensen; A Biedler; H van Beem; O Fraidakis; J H Silverstein; J E Beneken; J S Gravenstein
Journal:  Lancet       Date:  1998-03-21       Impact factor: 79.321

8.  Apolipoprotein E genotype and cognitive dysfunction after noncardiac surgery.

Authors:  Hanne Abildstrom; Michael Christiansen; Volkert D Siersma; Lars S Rasmussen
Journal:  Anesthesiology       Date:  2004-10       Impact factor: 7.892

9.  The association of intraoperative factors with the development of postoperative delirium.

Authors:  E R Marcantonio; L Goldman; E J Orav; E F Cook; T H Lee
Journal:  Am J Med       Date:  1998-11       Impact factor: 4.965

10.  Cognitive effects after epidural vs general anesthesia in older adults. A randomized trial.

Authors:  P Williams-Russo; N E Sharrock; S Mattis; T P Szatrowski; M E Charlson
Journal:  JAMA       Date:  1995-07-05       Impact factor: 56.272

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  144 in total

1.  Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain.

Authors:  Lana J Mawhinney; Juan Pablo de Rivero Vaccari; Ofelia F Alonso; Christopher A Jimenez; Concepción Furones; W Javier Moreno; Michael C Lewis; W Dalton Dietrich; Helen M Bramlett
Journal:  Brain Res       Date:  2011-11-07       Impact factor: 3.252

Review 2.  Translational approaches to treatment-induced symptoms in cancer patients.

Authors:  Robert Dantzer; Mary W Meagher; Charles S Cleeland
Journal:  Nat Rev Clin Oncol       Date:  2012-05-29       Impact factor: 66.675

Review 3.  Postoperative cognitive dysfunction in geriatric patients.

Authors:  K A Hartholt; T J M van der Cammen; M Klimek
Journal:  Z Gerontol Geriatr       Date:  2012-07       Impact factor: 1.281

4.  The impact of intravenous isotonic and hypotonic maintenance fluid on the risk of delirium in adult postoperative patients: retrospective before-after observational study.

Authors:  Masaharu Nagae; Moritoki Egi; Nana Furushima; Masako Okada; Shohei Makino; Satoshi Mizobuchi
Journal:  J Anesth       Date:  2019-02-26       Impact factor: 2.078

5.  Factors affecting the safety of drains and catheters in surgical patients.

Authors:  Kerim Bora Yılmaz; Melih Akıncı; Duray Şeker; Müjdat Güller; Gürkan Güneri; Hakan Kulaçoğlu
Journal:  Ulus Cerrahi Derg       Date:  2014-06-01

6.  Lower risk of postoperative delirium using laparoscopic approach for major abdominal surgery.

Authors:  Kyoji Ito; Yusuke Suka; Motoki Nagai; Keishi Kawasaki; Mariko Yamamoto; Daisuke Koike; Yukihiro Nomura; Nobutaka Tanaka; Yoshikuni Kawaguchi
Journal:  Surg Endosc       Date:  2019-01-14       Impact factor: 4.584

7.  Involvement of acute neuroinflammation in postoperative delirium-like cognitive deficits in rats.

Authors:  Takashi Kawano; Daiki Yamanaka; Bun Aoyama; Hiroki Tateiwa; Marie Shigematsu-Locatelli; Atsushi Nishigaki; Hideki Iwata; Fabricio M Locatelli; Masataka Yokoyama
Journal:  J Anesth       Date:  2018-05-03       Impact factor: 2.078

Review 8.  Perioperative delirium and its relationship to dementia.

Authors:  Jeffrey H Silverstein; Stacie G Deiner
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2012-12-06       Impact factor: 5.067

Review 9.  Factors Influencing Clinical Correlates of Chronic Traumatic Encephalopathy (CTE): a Review.

Authors:  Breton M Asken; Molly J Sullan; Aliyah R Snyder; Zachary M Houck; Vaughn E Bryant; Loren P Hizel; Molly E McLaren; Duane E Dede; Michael S Jaffee; Steven T DeKosky; Russell M Bauer
Journal:  Neuropsychol Rev       Date:  2016-08-25       Impact factor: 7.444

10.  Monitoring of cerebral blood flow autoregulation in adults undergoing sevoflurane anesthesia: a prospective cohort study of two age groups.

Authors:  Nicolai Goettel; Camille Patet; Ariane Rossi; Christoph S Burkhart; Marek Czosnyka; Stephan P Strebel; Luzius A Steiner
Journal:  J Clin Monit Comput       Date:  2015-08-19       Impact factor: 2.502

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