Literature DB >> 20006976

Antiviral flavonoids from Mosla scabra.

Qiaofeng Wu1, Chenhuan Yu, Yunliang Yan, Jing Chen, Chunchun Zhang, Xinxin Wen.   

Abstract

An ethanolic extract and ethyl acetate fraction (EFMS) prepared from Mosla scabra showed potential inhibition against influenza viruses. The compounds isolated from EFMS were elucidated to be ursolic acid (1), 5-hydroxy-6,7-dimethoxyflavone (2), 5-hydroxy-7,8-dimethoxyflavone (3), apigenin (4) and acacetin (5) based on their spectral analysis. Compounds 2, 3, 4 and 5 showed significant anti-influenza viruses activities. Compared with ribavirin, EFMS appeared to have similar efficacy against influenza viruses, was considered to be less toxic and may warrant further evaluation as a possible agent for the treatment of influenza. Copyright 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 20006976     DOI： 10.1016/j.fitote.2009.12.005

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  9 in total

1.  Inhibitory effects and related molecular mechanisms of total flavonoids in Mosla chinensis Maxim against H1N1 influenza virus.

Authors:  Xiao-Xia Zhang; Qiao-Feng Wu; Yun-Liang Yan; Feng-Ling Zhang
Journal:  Inflamm Res       Date:  2017-11-24       Impact factor: 4.575

2.  Anti-Inflammatory Mechanisms of Total Flavonoids from Mosla scabra against Influenza A Virus-Induced Pneumonia by Integrating Network Pharmacology and Experimental Verification.

Authors:  Wei Cai; Shui-Li Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2022-06-08       Impact factor: 2.650

3.  Network pharmacology study on the mechanism of the Chinese medicine Radix Isatidis (Banlangen) for COVID-19.

Authors:  Bin Yu; Fei Lin; Hong Ning; Baodong Ling
Journal:  Medicine (Baltimore)       Date:  2021-08-13       Impact factor: 1.817

4.  Daphne Genkwa sieb. Et zucc. Water-soluble extracts act on enterovirus 71 by inhibiting viral entry.

Authors:  Chia-Wen Chang; Yan-Lii Leu; Jim-Tong Horng
Journal:  Viruses       Date:  2012-04-11       Impact factor: 5.048

5.  Antiviral activities of atractylon from Atractylodis Rhizoma.

Authors:  Yang Cheng; Jing-Yin Mai; Tian-Lu Hou; Jian Ping; Jian-Jie Chen
Journal:  Mol Med Rep       Date:  2016-09-05       Impact factor: 2.952

Review 6.  A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota.

Authors:  Minqian Wang; Jenni Firrman; LinShu Liu; Kit Yam
Journal:  Biomed Res Int       Date:  2019-10-16       Impact factor: 3.411

Review 7.  Important Flavonoids and Their Role as a Therapeutic Agent.

Authors:  Asad Ullah; Sidra Munir; Syed Lal Badshah; Noreen Khan; Lubna Ghani; Benjamin Gabriel Poulson; Abdul-Hamid Emwas; Mariusz Jaremko
Journal:  Molecules       Date:  2020-11-11       Impact factor: 4.411

8.  Assessment of potency of PC-complexed Ocimum sanctum methanol extract in embryonated eggs against Influenza virus (H1N1).

Authors:  Priyanka Jadhav; Hingorani Lal; Nilima Kshirsagar
Journal:  Pharmacogn Mag       Date:  2014-01       Impact factor: 1.085

9.  Inhibitory effect of microalgae and cyanobacteria extracts on influenza virus replication and neuraminidase activity.

Authors:  Thauane Silva; Paulo S Salomon; Lidilhone Hamerski; Juline Walter; Rafael B Menezes; José Edson Siqueira; Aline Santos; Jéssica Aparecida Morais Santos; Natália Ferme; Thaise Guimarães; Giovana O Fistarol; Paulo I Hargreaves; Cristiane Thompson; Fabiano Thompson; Thiago Moreno Souza; Marilda Siqueira; Milene Miranda
Journal:  PeerJ       Date:  2018-10-26       Impact factor: 2.984
  9 in total

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