| Literature DB >> 20006835 |
Abstract
Natural Killer (NK) cells boost immune defense via their cytolytic activity and their capacity to produce interferon-gamma. Now Perona-Wright et al. (2009), in this issue of Cell Host & Microbe, show that NK cells can also dampen immune responses to diverse pathogens via secretion of the anti-inflammatory cytokine interleukin-10. Remarkably, this immunosuppressive activity only occurs during systemic infections.Entities:
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Year: 2009 PMID: 20006835 DOI: 10.1016/j.chom.2009.12.001
Source DB: PubMed Journal: Cell Host Microbe ISSN: 1931-3128 Impact factor: 21.023