| Literature DB >> 20005103 |
David C Blakemore1, Justin S Bryans, Pauline Carnell, Christopher L Carr, Nicola E A Chessum, Mark J Field, Natasha Kinsella, Simon A Osborne, Andrew N Warren, Sophie C Williams.
Abstract
Synthesis of a number of bicyclic five-membered ring derivatives of gabapentin led to the identification of two compounds, (-)-(11A) and (20A) which both had an excellent level of potency against alpha(2)delta and were profiled in an in vivo model of neuropathic pain. Copyright 2009 Elsevier Ltd. All rights reserved.Entities:
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Year: 2009 PMID： 20005103 DOI： 10.1016/j.bmcl.2009.11.118
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823