Literature DB >> 20004873

Alzheimer's disease: visual system review.

Denise A Valenti1.   

Abstract

BACKGROUND: Ten million baby boomers in the United States will get Alzheimer's disease. Optometrists can benefit from understanding the impact the Alzheimer's disease process has on the visual system. This can result in more effective management of the condition and in more effective communication with members of the Alzheimer's disease multidisciplinary team.
METHODS: This is a review of the literature but by no means a completely exhaustive review. Alzheimer's disease is a complex disease. A rapidly expanding body of knowledge covers multiple disciplines.
RESULTS: The visual system shows deficits early in the degenerative process of Alzheimer's disease. Biomarkers through the visual system such as nerve fiber deficits, lens opacities, and functional losses in the magnocellular pathway, such as contrast sensitivity and temporal processing, may prove to not only help detect Alzheimer's disease early but also detect it before there are the classic cognitive and memory losses.
CONCLUSIONS: The effects of Alzheimer's disease are devastating. Optometrists, as primary care clinicians, can make critical contributions in the diagnosis, treatment, and management of this neurodegenerative disease.

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Year:  2010        PMID: 20004873     DOI: 10.1016/j.optm.2009.04.101

Source DB:  PubMed          Journal:  Optometry        ISSN: 1558-1527


  18 in total

1.  Visual dysfunction and its correlation with retinal changes in patients with Alzheimer's disease.

Authors:  V Polo; M J Rodrigo; E Garcia-Martin; S Otin; J M Larrosa; M I Fuertes; M P Bambo; L E Pablo; M Satue
Journal:  Eye (Lond)       Date:  2017-03-10       Impact factor: 3.775

2.  The relationship between the degree of cognitive impairment and retinal nerve fiber layer thickness.

Authors:  Ece Ozdemir Oktem; Eda Derle; Seda Kibaroglu; Caglar Oktem; Imren Akkoyun; Ufuk Can
Journal:  Neurol Sci       Date:  2015-01-10       Impact factor: 3.307

3.  Alzheimer's disease and glaucoma: imaging the biomarkers of neurodegenerative disease.

Authors:  Denise A Valenti
Journal:  Int J Alzheimers Dis       Date:  2011-01-05

4.  Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints.

Authors:  Shannon L Risacher; Darrell Wudunn; Susan M Pepin; Tamiko R MaGee; Brenna C McDonald; Laura A Flashman; Heather A Wishart; Heather S Pixley; Laura A Rabin; Nadia Paré; Jessica J Englert; Eben Schwartz; Joshua R Curtain; John D West; Darren P O'Neill; Robert B Santulli; Richard W Newman; Andrew J Saykin
Journal:  Neurobiol Aging       Date:  2012-10-18       Impact factor: 4.673

Review 5.  Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?

Authors:  Kin Chiu; Tin-Fung Chan; Andrew Wu; Irene Yan-Pui Leung; Kwok-Fai So; Raymond Chuen-Chung Chang
Journal:  Age (Dordr)       Date:  2011-05-11

Review 6.  Myeloid cells in retinal and brain degeneration.

Authors:  Michelle Guo; Turner D Schwartz; Joshua L Dunaief; Qi N Cui
Journal:  FEBS J       Date:  2021-09-15       Impact factor: 5.622

7.  Thinner changes of the retinal nerve fiber layer in patients with mild cognitive impairment and Alzheimer's disease.

Authors:  Dachuan Liu; Lina Zhang; Zhen Li; Xuxiang Zhang; Yue Wu; Huiqing Yang; Baoquan Min; Xinqing Zhang; Daqing Ma; Yan Lu
Journal:  BMC Neurol       Date:  2015-02-21       Impact factor: 2.474

8.  Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer's Disease.

Authors:  Elena Salobrar-Garcia; Rosa de Hoz; Blanca Rojas; Ana I Ramirez; Juan J Salazar; Raquel Yubero; Pedro Gil; Alberto Triviño; José M Ramirez
Journal:  J Ophthalmol       Date:  2015-05-27       Impact factor: 1.909

Review 9.  Promise and challenge: the lens model as a biomarker for early diagnosis of Alzheimer's disease.

Authors:  Tian Tian; Boai Zhang; Yanjie Jia; Zhaoming Li
Journal:  Dis Markers       Date:  2014-02-12       Impact factor: 3.434

10.  The attenuation of retinal nerve fiber layer thickness and cognitive deterioration.

Authors:  Yuan Shen; Zhongyong Shi; Renbao Jia; Yikang Zhu; Yan Cheng; Wei Feng; Chunbo Li
Journal:  Front Cell Neurosci       Date:  2013-09-19       Impact factor: 5.505

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