Literature DB >> 20003045

Outcomes of transplants from patients with small renal tumours, live unrelated donors and dialysis wait-listed patients.

Nicholas R Brook1, Norma Gibbons, David W Johnson, David L Nicol.   

Abstract

We report the outcomes of renal transplant patients (n = 43) who received grafts from donors (n = 41) with small (<3 cm) renal tumours removed before transplantation covering the period from May 1996 to September 2007. Patient and graft survival were compared with the outcomes of conventional live unrelated transplants (LURTs) (n = 120) and to patient survival on the transplant waiting list for those who did not receive a kidney during this period (n = 153). Patient survival at 1, 3 and 5 years were 92%, 88% and 88% for recipients of tumourectomized kidneys (TKs), 99%, 97% and 97% for LURTs, and 98%, 92% and 74% for dialysis patients waiting for a deceased donor kidney (log rank score 10.4, P = 0.005). One patient experienced a local tumour recurrence at 9 years following transplantation. This patient declined intervention and is currently under active surveillance. Transplantation of tumourectomized kidneys from patients with small, localized, incidentally detected renal tumours results in similar outcomes to conventional LURTs and confers a significant survival advantage for patients who would otherwise be unable to receive a transplant.

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Year:  2009        PMID: 20003045     DOI: 10.1111/j.1432-2277.2009.01002.x

Source DB:  PubMed          Journal:  Transpl Int        ISSN: 0934-0874            Impact factor:   3.782


  9 in total

1.  Protecting transplant recipients and live renal donors: Facing the challenges.

Authors:  Ronald B Moore
Journal:  Can Urol Assoc J       Date:  2013 Jan-Feb       Impact factor: 1.862

Review 2.  Use of Kidneys with Small Renal Tumors for Transplantation.

Authors:  Alejandro Lugo-Baruqui; Giselle Guerra; Adriana Arocha; George W Burke; Gaetano Ciancio
Journal:  Curr Urol Rep       Date:  2016-01       Impact factor: 3.092

3.  Incidental renal cell carcinoma identified during laparoscopic live-related donor nephrectomy.

Authors:  John A Bycroft; Kapila S D Benaragama; Anna Green; Benjamin Lindsey; David L Nicol
Journal:  JRSM Short Rep       Date:  2010-09-20

Review 4.  Transplantation of kidneys with tumors.

Authors:  Giovanni M Frascà; Antonia D'Errico; Deborah Malvi; Camillo Porta; Laura Cosmai; Matteo Santoni; Silvio Sandrini; Chiara Salviani; Maurizio Gallieni; Emilio Balestra
Journal:  J Nephrol       Date:  2015-11-20       Impact factor: 3.902

5.  Renal transplantation with kidneys affected by tumours.

Authors:  Muhammad Arslan Khurram; Aliu Oladipupo Sanni; David Rix; David Talbot
Journal:  Int J Nephrol       Date:  2011-01-18

6.  Assessment of Restored Kidney Transplantation Including the Use of Wider Criteria for Accepting Renal Donors After Cancer Excision.

Authors:  Philip Sprott; Adrian D Hibberd; Munish K Heer; Paul R Trevillian; David A Clark; David W Johnson; Christopher Oldmeadow; Simon Chiu; John R Attia
Journal:  Transplant Direct       Date:  2019-10-08

Review 7.  Small renal masses in kidney transplantation: Overview of clinical impact and management in donors and recipients.

Authors:  Alberto Piana; Iulia Andras; Pietro Diana; Paolo Verri; Andrea Gallioli; Riccardo Campi; Thomas Prudhomme; Vital Hevia; Romain Boissier; Alberto Breda; Angelo Territo
Journal:  Asian J Urol       Date:  2022-06-10

8.  Transplant of kidneys with small renal cell carcinoma in incompatible, heavily immunosuppressed recipients.

Authors:  A M Ali; P Rajagoppal; A Sayed; N Hakim; T David; P Papalois
Journal:  Ann R Coll Surg Engl       Date:  2012-09       Impact factor: 1.891

9.  Benign and malignant renal cells are differentially inhibited during prolonged organ preservation.

Authors:  Nengwang Yu; Shuai Fu; Yubao Liu; Yibao Liu; Zhihou Fu; Jianzhong Meng; Zhonghua Xu; Baocheng Wang; Aimin Zhang
Journal:  PLoS One       Date:  2013-12-09       Impact factor: 3.240

  9 in total

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