| Literature DB >> 20001611 |
Abstract
Lamivudine is a nucleoside reverse transcriptase inhibitor that is widely used for the treatment of HIV-1 infection in combination with other antiretrovirals. It is a highly effective agent that can be dosed once or twice daily due to its long intracellular half-life. It also has one of the best tolerability and long-term safety profiles among all antiretroviral agents and continues to be preferred as part of initial or subsequent combination therapy in HIV-infected patients.Entities:
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Year: 2010 PMID: 20001611 DOI: 10.1517/17425250903490418
Source DB: PubMed Journal: Expert Opin Drug Metab Toxicol ISSN: 1742-5255 Impact factor: 4.481