BACKGROUND: Cognitive changes due to crack cocaine consumption remain unclear. METHODS: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. RESULTS: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). CONCLUSION: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.
RCT Entities:
BACKGROUND: Cognitive changes due to crack cocaine consumption remain unclear. METHODS: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out. RESULTS: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B). CONCLUSION: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.
Authors: Matthias Vonmoos; Lea M Hulka; Katrin H Preller; Franziska Minder; Markus R Baumgartner; Boris B Quednow Journal: Neuropsychopharmacology Date: 2014-03-21 Impact factor: 7.853
Authors: Porche K Henry; Annie Umbricht; Bethea A Kleykamp; Ryan Vandrey; Eric C Strain; George E Bigelow; Miriam Z Mintzer Journal: Drug Alcohol Depend Date: 2012-01-21 Impact factor: 4.492
Authors: André Q C Miguel; Clarice S Madruga; Hugo Cogo-Moreira; Rodolfo Yamauchi; Viviane Simões; Claudio J Da Silva; Renata R Abdalla; Michael McDonell; Sterling McPherson; John M Roll; Jair J Mari; Ronaldo R Laranjeira Journal: J Psychoactive Drugs Date: 2018-03-12
Authors: Sarah E Nigro; Minjie Wu; Anthony C Juliano; T Celeste Napier; Alan L Landay; Audrey L French; Shaolin Yang Journal: J Clin Exp Neuropsychol Date: 2022-07-04 Impact factor: 2.283
Authors: Pavel Y Litvin; Craig A Siders; Erin N Waite; Ellen Woo; Elizabeth Romero; Jessica Foley; Mark L Ettenhofer; Amanda L Gooding; Steven Castellon; Charles Hinkin; Matthew J Wright Journal: Appl Neuropsychol Adult Date: 2019-10-29 Impact factor: 2.248