Literature DB >> 20000753

Ni(II)-catalyzed enantioselective conjugate addition of acetylenes to alpha,beta-enones.

Oleg V Larionov1, E J Corey.   

Abstract

Alkynylaluminum reagents undergo enantioselective conjugate addition to cyclic alpha,beta-enones in the presence of chiral bisphosphine complexes of Ni(II).

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Year:  2010        PMID： 20000753     DOI： 10.1021/ol902643w

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  A new strategy for the synthesis of chiral β-alkynyl esters via sequential palladium and copper catalysis.

Authors:  Barry M Trost; Benjamin R Taft; James T Masters; Jean-Philip Lumb
Journal:  J Am Chem Soc       Date:  2011-05-16       Impact factor: 15.419

2.  Development of a Modular Synthetic Route to (+)-Pleuromutilin, (+)-12-epi-Mutilins, and Related Structures.

Authors:  Mingshuo Zeng; Stephen K Murphy; Seth B Herzon
Journal:  J Am Chem Soc       Date:  2017-11-02       Impact factor: 15.419

3.  Palladium-Catalyzed Enantioselective Redox-Relay Heck Alkynylation of Alkenols To Access Propargylic Stereocenters.

Authors:  Zhi-Min Chen; Christine S Nervig; Ryan J DeLuca; Matthew S Sigman
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-03       Impact factor: 15.336

4.  Enantioselective synthesis of alkyne-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed allylic substitution reactions with (i-Bu)2(alkynyl)aluminum reagents.

Authors:  Jennifer A Dabrowski; Fang Gao; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2011-03-08       Impact factor: 15.419

5.  Combining NHC-Cu and Brønsted base catalysis: enantioselective allylic substitution/conjugate additions with alkynylaluminum reagents and stereospecific isomerization of the products to trisubstituted allenes.

Authors:  Jennifer A Dabrowski; Fredrik Haeffner; Amir H Hoveyda
Journal:  Angew Chem Int Ed Engl       Date:  2013-06-18       Impact factor: 15.336

6.  Asymmetric synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives via sequential palladium and copper catalysis.

Authors:  Barry M Trost; James T Masters; Benjamin R Taft; Jean-Philip Lumb
Journal:  Chem Sci       Date:  2016-06-10       Impact factor: 9.825
  6 in total

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