| Literature DB >> 19996727 |
Eliza Martha de Paiva Barretto1, Monica Kayo, Belquiz S Avrichir, Antonio Reis Sa, Maria das Gracas Miquelutti Camargo, Isabel Cristina Napolitano, Fabiano Gonçalves Nery, Jony Arrais Pinto, Silvia Bannwart, Silvia Scemes, Elaine Di Sarno, Helio Elkis.
Abstract
The use of cognitive-behavior therapy (CBT) in addition to antipsychotic regimen to treat persistent psychotic symptoms of schizophrenia is growing. The aim of this study was to compare the efficacy of CBT to a befriending (BF) control group in patients with schizophrenia who are refractory to clozapine. Twenty-one patients completed the 21-week trial. In comparison with the control group, the CBT group showed a significant improvement in the General Psychopathology and total score of the Positive and Negative Syndrome Scale, as well as an improvement of Quality of Life scale. The improvement in psychopathology persisted at 6-month follow-up assessment.Entities:
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Year: 2009 PMID： 19996727 DOI： 10.1097/NMD.0b013e3181be7422
Source DB: PubMed Journal: J Nerv Ment Dis ISSN： 0022-3018 Impact factor: 2.254