Literature DB >> 19994476

Reversible enzymatic synthesis of flavin-adenine dinucleotide.

A W SCHRECKER, A KORNBERG.   

Abstract

An enzyme has been partially purified from brewer's yeast which catalyzes the reversible reaction between riboflavin phosphate and adenosine triphosphate (ATP) on the one hand and flavin-adenine dinucleotide (FAD) and inorganic pyrophosphate on the other in the presence of magnesium ions. ATP could not be replaced by adenosine diphosphate or adenosine-5-phosphate, and in the reverse reaction, inorganic pyrophosphate could not be replaced by ortho- or metaphosphate. With riboflavin and ATP a slight amount of FAD formation was observed.

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Year:  1950        PMID： 19994476

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  7 in total

1.  Flavin nucleotides and flavoproteins.

Authors:  F M HUENNEKENS
Journal:  Experientia       Date:  1956-01-15

2.  Flavines in experimental diabetes.

Authors:  F NAVAZIO; N SILIPRANDI
Journal:  Experientia       Date:  1955-07-15

3.  Synthesis and application of isotopically labeled flavin nucleotides.

Authors:  Tatiana V Mishanina; Amnon Kohen
Journal:  J Labelled Comp Radiopharm       Date:  2015-07-07       Impact factor: 1.921

Review 4.  Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.

Authors:  Charles A Abbas; Andriy A Sibirny
Journal:  Microbiol Mol Biol Rev       Date:  2011-06       Impact factor: 11.056

5.  Combined isobutyryl-CoA and multiple acyl-CoA dehydrogenase deficiency in a boy with altered riboflavin homeostasis.

Authors:  Albina Tummolo; Piero Leone; Maria Tolomeo; Rita Solito; Matteo Mattiuzzo; Francesca Romana Lepri; Tania Lorè; Roberta Cardinali; Donatella De Giovanni; Simonetta Simonetti; Maria Barile
Journal:  JIMD Rep       Date:  2022-05-07

Review 6.  Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy.

Authors:  Spencer G Miller; Paul S Hafen; Jeffrey J Brault
Journal:  Int J Mol Sci       Date:  2019-12-21       Impact factor: 5.923

7.  Bacterial over-expression and purification of the 3'phosphoadenosine 5'phosphosulfate (PAPS) reductase domain of human FAD synthase: functional characterization and homology modeling.

Authors:  Angelica Miccolis; Michele Galluccio; Teresa Anna Giancaspero; Cesare Indiveri; Maria Barile
Journal:  Int J Mol Sci       Date:  2012-12-11       Impact factor: 5.923
  7 in total

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