Literature DB >> 1996989

The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF.

Y Sato1, R Hamanaka, J Ono, M Kuwano, D B Rifkin, R Takaki.   

Abstract

The migration of arterial smooth muscle cells from the media to the intima is a crucial event for the development of the atherosclerotic lesion, and platelet derived growth factor (PDGF) is thought to play an important role in this process. Here we report that the spontaneous migration of bovine smooth muscle (BSM) cells is dependent on endogenously produced basic fibroblast growth factor (bFGF). PDGF stimulates the migration of BSM cells and its effect is abolished by affinity purified anti-bFGF antibody. PDGF induces bFGF mRNA in BSM cells. These results indicate that the effect of PDGF on the migration of BSM cells may be mediated by the induction of endogenous bFGF.

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Year:  1991        PMID： 1996989     DOI： 10.1016/0006-291x(91)91557-s

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  13 in total

1.  TGF-beta 1 reverses PDGF-stimulated migration of human aortic smooth muscle cells in vitro.

Authors:  L Engel; U Ryan
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-06       Impact factor: 2.416

2.  Molecular atherectomy for restenosis.

Authors:  W Casscells; D A Lappi; A Baird
Journal:  Trends Cardiovasc Med       Date:  1993 Nov-Dec       Impact factor: 6.677

3.  Elevated expression of basic fibroblast growth factor in an immortalized rabbit smooth muscle cell line.

Authors:  J A Winkles; R Friesel; G F Alberts; M F Janat; G Liau
Journal:  Am J Pathol       Date:  1993-08       Impact factor: 4.307

4.  EGFL7 is a chemoattractant for endothelial cells and is up-regulated in angiogenesis and arterial injury.

Authors:  Luisa Campagnolo; Amy Leahy; Smita Chitnis; Stefan Koschnick; Michael J Fitch; John T Fallon; David Loskutoff; Mark B Taubman; Heidi Stuhlmann
Journal:  Am J Pathol       Date:  2005-07       Impact factor: 4.307

5.  Sequence-independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides.

Authors:  W Wang; H J Chen; A Schwartz; P J Cannon; C A Stein; L E Rabbani
Journal:  J Clin Invest       Date:  1996-07-15       Impact factor: 14.808

Review 6.  Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling.

Authors:  Eric A Severson; Charles A Parkos
Journal:  Curr Opin Cell Biol       Date:  2009-07-14       Impact factor: 8.382

7.  Autonomous migration of human fetal skin fibroblasts into a denuded area in a cell monolayer is mediated by basic fibroblast growth factor and collagen.

Authors:  H Kondo; R Matsuda; Y Yonezawa
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-12       Impact factor: 2.416

8.  Heparin and dibutyryl cAMP modulate gene expression in stimulated human saphenous vein smooth muscle cells.

Authors:  M Yamaguchi; S Diamond; H Watanabe; H Gallati; W Baur; J B Sharefkin
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-11       Impact factor: 2.416

9.  Basic fibroblast growth factor: its role in the control of smooth muscle cell migration.

Authors:  C L Jackson; M A Reidy
Journal:  Am J Pathol       Date:  1993-10       Impact factor: 4.307

10.  Intracellular signaling pathways required for rat vascular smooth muscle cell migration. Interactions between basic fibroblast growth factor and platelet-derived growth factor.

Authors:  C Bilato; R R Pauly; G Melillo; R Monticone; D Gorelick-Feldman; Y A Gluzband; S J Sollott; B Ziman; E G Lakatta; M T Crow
Journal:  J Clin Invest       Date:  1995-10       Impact factor: 14.808
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